4-(4-Bromo-2-methylphenyl)thiazole-2-carboxylic acid CAS 886367-14-2

Description

The occurrence of 4-(4-Bromo-2-methylphenyl)thiazole-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(4-Bromo-2-methylphenyl)thiazole-2-carboxylic acid (CAS 886367-14-2), molecular formula C11H8BrNO2S and molecular weight 298.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(4-Bromo-2-methylphenyl)thiazole-2-carboxylic acid (C11H8BrNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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