2-Amino-3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-3-methylbutanoic acid CAS 88643-32-7
| CAS No. | 88643-32-7 |
| Molecular Formula | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-3-methylbutanoic acid.
2-Amino-3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-3-methylbutanoic acid (CAS 88643-32-7) is a high-purity analytical reference standard with the molecular formula C15H22N6O5S and a molecular weight of 398.44 g/mol.
2-Amino-3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-3-methylbutanoic acid (C15H22N6O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22N6O5S |
| Molecular Weight | 398.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Amino Standards
- (S)-2-Amino-4-((((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl)thio)butanoic acid (CAS 50698-77-6)
- 2-Amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-2-methylbutanoic acid (CAS 61102-32-7)
- 3-Amino-N-(4-methylthiazol-2-yl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626222-24-0)
- 2-Amino-6-methyl-5-(4-phenylbutyl)pyrimidin-4(3H)-one (CAS 1596-98-1)
- Ethyl (8-amino-3-(3,4,5-trimethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl)carbamate (CAS 28642-77-5)
- N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide (CAS 149981-36-2)
- 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 610259-29-5)
- Methyl 2-amino-4-(2,5-dichlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 898921-20-5)
Recommended Standards
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 618879-94-0)
- 2-Methoxy-4-(((3-(2-methoxyphenyl)-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)imino)methyl)phenyl acetate (CAS 478257-24-8)
- (3-((4-Methoxyphenyl)sulfonyl)azetidin-1-yl)(2-phenyl-2H-1,2,3-triazol-4-yl)methanone (CAS 1797276-06-2)
- Adenine Impurity 16 (CAS 78548-84-2)
- N-(2,3-Dibromopropyl)-N-formylformic hydrazide (CAS 216854-54-5)
- 1-(Piperidin-4-yl)azetidin-3-ol (CAS 1147423-04-8)
- 3-(4-Methylcyclohexyl)acrylaldehyde (CAS 6739-05-5)
- n-(Pyrimidin-2-ylmethyl)ethanamine (CAS 1199780-89-6)
- 4-Cyclopropoxy-N-methyl-5-nitropicolinamide (CAS 1243348-47-1)
- 1-[2-(4-Methoxyphenyl)ethyl]-5-oxo-3-pyrrolidinecarboxylic acid (CAS 85263-81-6)
- Diethyl allyl phosphate (CAS 1067-87-4)
- 1-(tert-Butyl) 2-methyl (2S,4S)-4-amino-1,2-pyrrolidinedicarboxylate hydrochloride (CAS 1922671-53-1)
- 3,5-Dibromo-4-propylpyridin-2-amine (CAS 2009273-75-8)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com