N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide CAS 149981-36-2
| CAS No. | 149981-36-2 |
| Molecular Formula | C18H21F3N4O3 |
| Molecular Weight | 398.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide (CAS 149981-36-2) is a high-purity analytical reference standard with the molecular formula C18H21F3N4O3 and a molecular weight of 398.38 g/mol.
The molecular framework of N-(6-Amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(trifluoromethyl)benzamide (C18H21F3N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H21F3N4O3 |
| Molecular Weight | 398.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- Ethyl (8-amino-3-(3,4,5-trimethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl)carbamate (CAS 28642-77-5)
- 3-Amino-N-(4-methylthiazol-2-yl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626222-24-0)
- (S)-2-Amino-4-((((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl)thio)butanoic acid (CAS 50698-77-6)
- 2-Amino-3-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-3-methylbutanoic acid (CAS 88643-32-7)
- 2-Amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)-2-methylbutanoic acid (CAS 61102-32-7)
- 2-Amino-6-methyl-5-(4-phenylbutyl)pyrimidin-4(3H)-one (CAS 1596-98-1)
- 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 610259-29-5)
- Methyl 2-amino-4-(2,5-dichlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 898921-20-5)
Recommended Standards
- N-[9-(2-Hydroxyethyl)-9H-carbazol-3-yl]-2-(trifluoromethyl)benzamide (CAS 1195786-61-8)
- 2-(4-((4-(Trifluoromethyl)benzyl)oxy)phenyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 477888-33-8)
- Cariprazine Impurity 43 (CAS 1092822-52-0)
- 2-(4-Methoxyphenyl)-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (CAS 339009-79-9)
- 5-phenyl-2,3-dihydro-1,3-thiazol-2-one (CAS 83631-55-4)
- 1-(2-Methylpropyl)-piperidine (CAS 10315-89-6)
- Magnesium Metaphosphate (CAS 13573-12-1)
- 1-(2-Cyclopropyl-5,6,7,8-tetrahydroquinazolin-4-yl)pyrrolidin-3-amine (CAS 1707594-71-5)
- 2-Chloro-5-(4-methoxyphenyl)oxazole (CAS 1060816-32-1)
- 2-(Pyrrolidin-2-yl)pyrimidine-4-carbaldehyde (CAS 944900-56-5)
- 6-Fluoro-1,2,3,4-tetrahydroisoquinoline (CAS 224161-37-9)
- 6-Bromo-7-methyl-1H-benzo[d][1,2,3]triazole (CAS 1372795-26-0)
- 2-(4-Hydroxy-3-methoxy-5-nitrophenyl)acetic acid (CAS 88516-84-1)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
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