(4,5-Difluoro-2-methoxyphenyl)methanamine CAS 886497-93-4
| CAS No. | 886497-93-4 |
| Molecular Formula | C8H9F2NO |
| Molecular Weight | 173.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 173.16 g/mol gives (4,5-Difluoro-2-methoxyphenyl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4,5-Difluoro-2-methoxyphenyl)methanamine (CAS 886497-93-4) is a high-purity analytical reference standard with the molecular formula C8H9F2NO and a molecular weight of 173.16 g/mol.
The molecular framework of (4,5-Difluoro-2-methoxyphenyl)methanamine (C8H9F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9F2NO |
| Molecular Weight | 173.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- (2,5-Difluoro-4-methoxyphenyl)methanamine (CAS 1024491-40-4)
- (3,5-Difluoro-4-methoxyphenyl)methanamine (CAS 105969-16-2)
- (3,6-Difluoro-2-methoxyphenyl)methanamine (CAS 1261776-19-5)
- 2,3-Difluoro-5-methoxy-4-methylaniline (CAS 1706446-33-4)
- 5,5-Difluoro-4,5,6,7-tetrahydro-1H-indazol-3-amine (CAS 1785523-30-9)
- (2,3-Difluoro-4-methoxyphenyl)methanamine (CAS 886500-75-0)
- (2,6-Difluoro-3-methoxyphenyl)methanamine (CAS 886498-50-6)
- (2,6-Difluoro-4-methoxyphenyl)methanamine (CAS 771573-20-7)
Recommended Standards
- (3,5-Difluoro-2-methoxyphenyl)methanamine (CAS 886502-00-7)
- (R)-2-Amino-2-(3,4-difluorophenyl)ethan-1-ol (CAS 277295-93-9)
- (3-(Difluoromethoxy)phenyl)methanamine (CAS 244022-71-7)
- (R)-2-Amino-2-(3,5-difluorophenyl)ethanol (CAS 957121-38-9)
- 8-Methoxy-1-(2-oxopropyl)quinolin-4(1H)-one (CAS 1209326-62-4)
- N-(4-fluoro-3-nitrophenyl)-2-(pyridin-2-ylthio)acetamide (CAS 401574-09-2)
- 1-(2-(Naphthalen-2-yl)quinolin-4-yl)ethanone (CAS 6317-99-3)
- Ethyl 4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate (CAS 96986-78-6)
- Pci-29732 (CAS 330786-25-9)
- 2,3-Dimethylquinoxalin-6-amine (CAS 7576-88-7)
- (Furan-3-yloxy)trimethylsilane (CAS 107638-06-2)
- (2-Phenylpropyl)(prop-2-en-1-yl)amine (CAS 932154-41-1)
- 1,4-Difluoro-2-(3-methylbut-3-en-1-yl)benzene (CAS 951892-35-6)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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