2-(2-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile CAS 886497-94-5

Purity 97%+In StockPharmaceutical Standards
CAS No.886497-94-5
Molecular FormulaC9H5F4NO
Molecular Weight219.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile CAS 886497-94-5 chemical structure

Description

2-(2-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile (CAS 886497-94-5), molecular formula C9H5F4NO and molecular weight 219.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile (C9H5F4NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(2-Fluoro-5-(trifluoromethoxy)phenyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H5F4NO
Molecular Weight219.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms1

Related Fluoro Standards

Recommended Standards

Why CATO?