2-(Methylsulfonyl)-3-(trifluoromethyl)pyridine CAS 886498-06-2
| CAS No. | 886498-06-2 |
| Molecular Formula | C7H6F3NO2S |
| Molecular Weight | 225.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Methylsulfonyl)-3-(trifluoromethyl)pyridine.
2-(Methylsulfonyl)-3-(trifluoromethyl)pyridine (CAS 886498-06-2) is a high-purity analytical reference standard with the molecular formula C7H6F3NO2S and a molecular weight of 225.19 g/mol.
2-(Methylsulfonyl)-3-(trifluoromethyl)pyridine (C7H6F3NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Methylsulfonyl)-3-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO2S |
| Molecular Weight | 225.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methylsulfonyl Standards
- 2-(Methylsulfonyl)-5-(trifluoromethyl)pyridine (CAS 178204-50-7)
- 1-(Methylsulfonyl)indoline-2,3-dione (CAS 58837-08-4)
- 2-(Methylsulfonyl)pyrido[2,3-d]pyrimidin-7(1H)-one (CAS 211244-92-7)
- 4-Methylsulfonyl-2-nitrofluorobenzene 2-fluoro-5-methylsulphonyl nitrobenzene 1-fluoro-4-methanesulfonyl-2-nitro-benzene 2-fluoro-5-methylsulfonylnitrobenzene 1-fluoro-4-methylsulfonyl-2-nitrobenzene 2-fluoro-5-methyl sulfonyl nitrobenzene 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene 2-fluoro-5-methylsulphonylnitrobenzene 1-fluoro-4-(methylsulphonyl)-2-nitrobenzene (3-Nitro-4-fluorophenyl)methyl sulfone 1-Fluoro-4-methanesulfonyl-2-nitrobenzene 4-Fluoro-3-nitrophenyl methyl sulfone 453-72-5 (CAS 453-72-5)
- 1-(Methylsulfonyl)-2,3-dihydroquinolin-4(1H)-one (CAS 22366-61-6)
- N-(4-(methylsulfonyl)phenyl)acrylamide (CAS 852146-99-7)
- 2-(3-(Methylsulfonyl)phenyl)pyrrolidine (CAS 1016521-37-1)
- 2-(4-(Methylsulfonyl)phenyl)pyrrolidine (CAS 1016751-26-0)
Recommended Standards
- 1-Benzyl-3,3-difluoropyrrolidine-2,5-dione (CAS 862416-33-9)
- 2-Amino-5-(2,2,2-trifluoroethyl)thiophene-3-carboxylic Acid (CAS 2166754-63-6)
- 1-(2,4-Difluorophenyl)-3,4-dimethyl-1H-1,2,4-triazol-5(4H)-one (CAS 90208-66-5)
- 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-carbohydrazide (CAS 338978-09-9)
- N-(5-Cyclopropylisoxazol-3-yl)formamide (CAS 55809-17-1)
- 2-(2’-Hydroxyphenoxy)-4-nitro-benzophenone (CAS 1329834-07-2)
- 2-Ethoxyquinolin-4-amine (CAS 50786-32-8)
- 2-Fluoro-7,8-dihydro-1,6-naphthyridin-5(6H)-one (CAS 1260666-31-6)
- Methyl 2-(methyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinecarboxylate (CAS 1083168-93-7)
- 1-Methyl-4-(4-(4-(3-(piperidin-4-ylmethoxy)pyridin-4-yl)-1H-pyrazol-1-yl)phenyl)piperazine hydrochloride (CAS 2096992-20-8)
- (2S,5R,6S)-Methyl 6-bromo-6-((R)-1-hydroxyethyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (CAS 80629-46-5)
- 4-(2-Methyl-1-piperidinyl)-3-nitrobenzoic acid (CAS 1019461-42-7)
- (s)-2-Amino-2-(4-fluoro-3-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1213413-72-9)
- (D-Tyr1,N-Me-Phe3)-Neuropeptide FF (H-4752.0001) (CAS 145274-93-7)
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