3-(2,3-Difluoro-4-methoxyphenyl)propanoic acid CAS 886499-84-9
| CAS No. | 886499-84-9 |
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 216.18 g/mol gives 3-(2,3-Difluoro-4-methoxyphenyl)propanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(2,3-Difluoro-4-methoxyphenyl)propanoic acid (CAS 886499-84-9), molecular formula C10H10F2O3 and molecular weight 216.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(2,3-Difluoro-4-methoxyphenyl)propanoic acid (C10H10F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 216.18 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2,3-Difluoro-4-methoxyphenyl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O3 |
| Molecular Weight | 216.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoro Standards
- Ethyl 3,5-difluoro-2-methoxybenzoate (CAS 1008138-31-5)
- 3-(3,5-Difluoro-4-methoxyphenyl)propanoic acid (CAS 105219-44-1)
- 3-(3,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-64-4)
- 3-(4,5-Difluoro-2-methoxyphenyl)propanoic acid (CAS 1092460-69-9)
- methyl 4-(2,2-difluoro-1-hydroxyethyl)benzoate (CAS 1176283-75-2)
- 2,4-Difluoro-3-(1-methylethoxy)benzoic acid (CAS 1219020-69-5)
- 2,3-Difluoro-6-nitro-n-propylaniline (CAS 1250052-21-1)
- Ethyl 3,4-difluoro-5-methoxybenzoate (CAS 1256469-95-0)
Recommended Standards
- 2-[4-(2,2-difluoroethoxy)phenyl]acetic acid (CAS 937602-66-9)
- 3-(2,5-Difluoro-4-(hydroxymethyl)phenyl)oxetan-3-ol (CAS 2168950-56-7)
- 2-[3-(difluoromethyl)-1h,4h,5h,6h-cyclopenta[c]pyrazol-1-yl]acetic acid (CAS 937599-56-9)
- 3-(3,4-Difluoro-5-methoxyphenyl)propanoic acid (CAS 881190-53-0)
- 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine 2-(9-oxo-9H-xanthen-2-yl)propanoate (CAS 1346753-09-0)
- N-Methyl-2,3-dihydro-1,4-benzodioxine-5-carboxamide (CAS 1203954-92-0)
- 8-Hydroxyquinoline-7-carbaldehyde (CAS 5683-78-3)
- 4-Chloro-2-pyrrolidinobenzoic Acid (CAS 1197193-20-6)
- (S)-FMOC-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic acid (CAS 141636-66-0)
- Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate (CAS 735319-21-8)
- 4-Chloro-1-(4-(trifluoromethoxy)phenyl)butan-1-one (CAS 898761-60-9)
- Trifluridine/tipiracil (TAS-102) Impurity D (CAS 91447-90-4)
- (1,4-Diazepan-1-yl)(2,6-dichlorophenyl)methanone hydrochloride (CAS 1606930-69-1)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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