Ethyl 7-amino-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate CAS 886762-57-8
| CAS No. | 886762-57-8 |
| Molecular Formula | C17H15F3N4O2 |
| Molecular Weight | 364.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ethyl 7-amino-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 886762-57-8), molecular formula C17H15F3N4O2 and molecular weight 364.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 7-amino-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (C17H15F3N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15F3N4O2 |
| Molecular Weight | 364.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- 5-Amino-1-(2-fluorophenyl)-N-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxamide (CAS 955964-66-6)
- 5-Amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 110236-78-7)
- 5-Amino-7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 112654-98-5)
- Ethyl 2-(1-amino-2-(ethoxycarbonyl)-3-oxobut-1-en-1-yl)-4-carbamoyl-6-methylpyrimidine-5-carboxylate (CAS 79593-42-3)
- 2-Amino-6-(hydroxymethyl)-8-oxo-4-(2-(trifluoromethyl)phenyl)-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 697246-16-5)
- 2-Amino-6-(hydroxymethyl)-8-oxo-4-(3-(trifluoromethyl)phenyl)-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 695203-79-3)
- Methyl 5-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-3-phenyl-1,2-oxazole-4-carboxylate (CAS 338966-64-6)
- Methyl 2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-3-(2,4-dichlorophenyl)propanoate (CAS 899726-09-1)
Recommended Standards
- 7-Phenyl-2-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 439108-39-1)
- Methyl 2-(benzoylamino)-3-[3-(trifluoromethyl)anilino]acrylate (CAS 338785-15-2)
- 7-Hydroxy-3-(4-propylphenoxy)-2-(trifluoromethyl)-4h-chromen-4-one (CAS 315233-03-5)
- S-99 (CAS 1124381-69-6)
- Methyl [3,3'-bipyridine]-6-carboxylate (CAS 1214390-27-8)
- 测试-适应性样品 (CAS CATO-C4X-25095)
- 6-Methyl-2-(2-methylquinolin-6-yl)benzo[d]thiazole-7-sulfonic acid (CAS 3181-86-0)
- Salbutamol Impurity 196 (CAS CATO-C4X-1176196)
- Imrecoxib Impurity 77 (CAS CATO-C4X-237977)
- (R)-2-(4-(2-Chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(1-((R)-2,3-dihydroxypropyl)-1H-pyrazol-3-yl)-4-methylpentanamide(relative) (CAS 1830307-01-1)
- 5-Bromopent-2-yne (CAS 18719-27-2)
- (4S,4′S)-2,2′-[(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis[4,5-dihydro-4-phenyloxazole] (CAS 182966-74-1)
- Osimertinib Impurity 74 (CAS CATO-C4X-204574)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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