Osimertinib Impurity 74 CAS CATO-C4X-204574
| CAS No. | CATO-C4X-204574 |
| Molecular Formula | C20H18FN5O |
| Molecular Weight | 363.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Osimertinib Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Osimertinib Impurity 74 (CAS CATO-C4X-204574), a pharmacopoeial impurity reference standard (molecular formula C20H18FN5O, MW 363.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H18FN5O, Osimertinib Impurity 74 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 363.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H18FN5O |
| Molecular Weight | 363.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Osimertinib Standards
- Osimertinib Impurity 69 (CAS CATO-C4X-204569)
- Osimertinib Impurity 70 (CAS CATO-C4X-204570)
- Osimertinib Impurity 17 (CAS CATO-C4X-204517)
- Osimertinib Impurity 76 (CAS CATO-C4X-204576)
- Osimertinib Impurity 77 (CAS CATO-C4X-204577)
- Osimertinib Impurity 89 (CAS CATO-C4X-204589)
- Osimertinib Impurity 87 (CAS CATO-C4X-204587)
- Osimertinib Impurity 36 (CAS CATO-C4X-204536)
Recommended Standards
- Torasemide Impurity 44 (CAS CATO-C4X-183644)
- N-Nitroso Penicillenic Acid (CAS CATO-C4X-30961)
- Cephalexin Impurity 42 (CAS 52210-38-5)
- Cefadroxil (CAS 50370-12-2)
- Fosaprepitant Impurity 21 (CAS 265121-01-5)
- Alanyl Glutamine impurity 49 (CAS 656221-79-3（free base)）)
- Spironolactone EP Impurity F (CAS 976-71-6)
- Androsta-3,5,16-trien-17-ol Trifluoromethanesulfonate (CAS 154229-36-4)
- K4C08XP666 7758-87-4 Calcium orthophosphate Calcium phosphate, tribasic Phosphoric acid, calcium salt (2:3) Tricalcium phosphate Calcium phosphate, tribasic [NF] Calcium phosphate tribasic Tricalcium bis(orthophosphate), with a fluorine content of less than 0,005 % by weight on the dry anhydrous product Tricalcium bis(orthophosphate) Bonarka Calcigenol simple Calcium orthophosphate, tri-(tert) Calcium phosphate Calcium phosphate (3:2) Calcium phosphate (Ca3(PO4)2) Calcium tertiary phosphate Caswell No. 148 CCRIS 3668 EINECS 231-840-8 EPA Pesticide Chemical Code 076401 FEMA No. 3081 HSDB 879 Natural whitlockite Phosphoric acid calcium(2+) salt (2:3) Synthos Tertiary calcium phosphate Tribasic calcium phosphate Tricalcium diphosphate Tricalcium orthophosphate Tricalcium phosphate (Ca3(PO4)2) UNII-K4C08XP666 Tricafos P TCP Ostram Posture (calcium supplement) Calipharm T Cerasorb Osferion Vitoss TricOs Synthograft Multifos JAX TCP Ceredex EC 231-840-8 beta-Tricalcium phosphate beta-TCP (CAS 7758-87-4)
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Why CATO?
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