4-(4-Chlorobenzyl)-7-isopropoxy-6-methoxyisoquinoline CAS 88708-12-7
| CAS No. | 88708-12-7 |
| Molecular Formula | C20H20ClNO2 |
| Molecular Weight | 341.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Chlorobenzyl)-7-isopropoxy-6-methoxyisoquinoline.
CATO supplies 4-(4-Chlorobenzyl)-7-isopropoxy-6-methoxyisoquinoline (CAS 88708-12-7), a certified reference material (molecular formula C20H20ClNO2, MW 341.83 g/mol) for analytical method development and quality control.
4-(4-Chlorobenzyl)-7-isopropoxy-6-methoxyisoquinoline (C20H20ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H20ClNO2 |
| Molecular Weight | 341.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- 4-(4-Chlorobenzyl)-1-ethyl-6,7-dimethoxyisoquinoline (CAS 62334-27-4)
- 4-(4-Chlorobenzyl)-3-ethyl-6,7-dimethoxyisoquinoline (CAS 62334-41-2)
- 4-(4-Chlorobenzyl)-6-isopropoxy-7-methoxyisoquinoline (CAS 88708-11-6)
- 5-((3-Chlorobenzyl)thio)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 477889-49-9)
- 6-((4-Chlorobenzyl)thio)-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (CAS 889950-49-6)
- 1-(2-chlorobenzyl)-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 937598-76-0)
- 1-(4-chlorobenzyl)-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 937598-70-4)
- 3-(4-Chlorobenzyl)-4-hydroxy-1-(4-methoxyphenyl)pyridin-2(1H)-one (CAS 477846-49-4)
Recommended Standards
- 4-(4-Chlorophenyl)-3,7,7-trimethyl-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one (CAS 370588-24-2)
- 4-(5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid (CAS 614737-09-6)
- 5-[(2-Chlorophenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinebutanoic acid (CAS 301158-16-7)
- 3-Chloro-N-(2-methyl-1-(6-methyl-1H-benzo[d]imidazol-2-yl)propyl)benzamide (CAS 338422-99-4)
- 3-[2-(propan-2-yl)-1H-imidazol-1-yl]propanoic acid (CAS 462068-54-8)
- 3-[4-(Propan-2-yl)benzenesulfonyl]-4H,5H-[1,2,3]triazolo[1,5-a]quinazolin-5-one (CAS 866350-26-7)
- 1-Methyl-1H-1,2,4-triazole-3-thiol (CAS 29983-22-0)
- 4-Amino-2-(cyclopropylmethoxy)benzamide (CAS 1343847-18-6)
- 3,4-Dichlorocinnamic Acid (CAS 1202-39-7)
- 1-(2-Aminoethyl)pyrimidine-2,4(1h,3h)-dione (CAS 34386-72-6)
- 2-Amino-8-bromopurineriboside (CAS 3001-47-6)
- 168890-46-8 2-(4-Methoxy-phenyl)-azepane 5434AD C13H19NO (CAS 168890-46-8)
- 2-Chloro-3-ethoxy-6-fluorobenzaldehyde (CAS 181305-73-7)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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