5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione CAS 88740-57-2

Purity 97%+In StockPharmaceutical Standards
CAS No.88740-57-2
Molecular FormulaC10H6FN3O3
Molecular Weight235.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione CAS 88740-57-2 chemical structure

Description

The occurrence of 5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione (CAS 88740-57-2), a certified reference material (molecular formula C10H6FN3O3, MW 235.17 g/mol) for analytical method development and quality control.

5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione (C10H6FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H6FN3O3
Molecular Weight235.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentF-containing
Nitrogen Atoms3

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