2-((5-Iodo-2-methylquinolin-8-yl)oxy)acetonitrile CAS 88757-50-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-Iodo-2-methylquinolin-8-yl)oxy)acetonitrile.

2-((5-Iodo-2-methylquinolin-8-yl)oxy)acetonitrile (CAS 88757-50-0) is a high-purity analytical reference standard with the molecular formula C12H9IN2O and a molecular weight of 324.12 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, 2-((5-Iodo-2-methylquinolin-8-yl)oxy)acetonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 324.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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