1-(3-(Trifluoromethyl)phenyl)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-thione 5,5-dioxide CAS 887833-92-3
| CAS No. | 887833-92-3 |
| Molecular Formula | C12H11F3N2O2S2 |
| Molecular Weight | 336.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(3-(Trifluoromethyl)phenyl)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-thione 5,5-dioxide (C12H11F3N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-(3-(Trifluoromethyl)phenyl)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-thione 5,5-dioxide (CAS 887833-92-3), molecular formula C12H11F3N2O2S2 and molecular weight 336.35 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3-(Trifluoromethyl)phenyl)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-thione 5,5-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11F3N2O2S2 |
| Molecular Weight | 336.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Trifluoromethyl Standards
- (2E)-2-({[3-(trifluoromethyl)phenyl]amino}methylidene)-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 478042-63-6)
- [1-(trifluoromethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]methyl 4-methylbenzenesulfonate (CAS 2770347-99-2)
- 1-((2-(Trifluoromethyl)phenyl)sulfonyl)piperidine-4-carboxamide (CAS 878909-79-6)
- 2-Phenyl-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole (CAS 477846-61-0)
- 4-(2-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197052-41-6)
- 4-(3-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197062-13-6)
- 4-(4-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197056-70-3)
- 4-{4-Methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (CAS 499795-87-8)
Recommended Standards
- (1S,2S,3R)-Diethyl 3-(4-fluorophenyl)-4-oxocyclohexane-1,2-dicarboxylate (CAS 860642-62-2)
- 2-((4,6-Bis(phenylamino)-1,3,5-triazin-2-yl)amino)acetic acid (CAS 62751-85-3)
- TLR7-agonist-1 (CAS 1642857-69-9)
- 2-(Ethylsulfonyl)-4-(5-methylthiophen-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 832737-60-7)
- Tert-butyl 4-hydroxy-2-azabicyclo[2.1.1]Hexane-2-carboxylate (CAS 2408971-50-4)
- 1-((2-Methylthiazol-4-yl)methyl)-1H-pyrazol-3-amine (CAS 1372891-97-8)
- cis-3-methoxycyclopentanamine (CAS 1268522-02-6)
- (S)-1-(pyrrolidin-2-yl)ethan-1-one (CAS 120966-82-7)
- 2-(Benzo[b]thiophen-3-yl)-2-(dimethylamino)acetic acid (CAS 1007879-04-0)
- (R)-2,2,2-Trifluoro-1-(4-phenoxyphenyl)ethan-1-amine (CAS 1212964-18-5)
- Spiro[4.4]nonan-1-amine (CAS 20440-71-5)
- 2,6,10-Trimethyl-2,6,10-triazaundecane (CAS 3855-32-1)
- 3-Bromo-4-(cyclohexyloxy)benzoic acid (CAS 1131594-47-2)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
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