5-(2,4-Difluorophenyl)thiophene-2-carbaldehyde CAS 887986-73-4
| CAS No. | 887986-73-4 |
| Molecular Formula | C11H6F2OS |
| Molecular Weight | 224.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2,4-Difluorophenyl)thiophene-2-carbaldehyde (CAS 887986-73-4) is a high-purity analytical reference standard with the molecular formula C11H6F2OS and a molecular weight of 224.23 g/mol.
Owing to sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 5-(2,4-Difluorophenyl)thiophene-2-carbaldehyde is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 224.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(2,4-Difluorophenyl)thiophene-2-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6F2OS |
| Molecular Weight | 224.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluorophenyl Standards
- (3,4-Difluorophenyl)(thiophen-3-yl)methanone (CAS 898771-62-5)
- (3,5-Difluorophenyl)(thiophen-3-yl)methanone (CAS 898771-64-7)
- 5-(2,3-Difluorophenyl)thiophene-2-carbaldehyde (CAS 887987-08-8)
- 2-(2,4-Difluorophenyl)-1-(4H-1,2,4-triazol-3-yl)ethan-1-amine (CAS 1490975-40-0)
- 2-(3,4-Difluorophenyl)cycloheptan-1-one (CAS 1341752-75-7)
- (3,4-Difluorophenyl)(5-methylfuran-2-yl)methanol (CAS 1250381-15-7)
- (3,5-Difluorophenyl)(5-methylfuran-2-yl)methanol (CAS 1343189-28-5)
- 5-(2,3-Difluorophenyl)cyclohexane-1,3-dione (CAS 1503065-06-2)
Recommended Standards
- 5-(3-Fluoro-2-methylphenyl)-5-oxopentanoic acid (CAS 951892-62-9)
- 4-methyl-6-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-3-amine (CAS 832740-69-9)
- 5-(3-Fluoro-4-methylphenyl)-5-oxopentanoic acid (CAS 898765-93-0)
- 4-Hydroxynaphthalene-2-sulfonic acid (CAS 3771-14-0)
- 2-(4-Bromo-3-formylphenoxy)-benzonitrile (CAS 1160182-46-6)
- 6-(Methylthio)-9-(tetrahydrothiophen-2-yl)-9H-purine (CAS 51776-58-0)
- 2-[2-(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 517864-11-8)
- (2,4-Dichloro-6-hydroxyphenyl)boronic acid (CAS 1028332-22-0)
- 3-[(2-Chloro-4-methoxyphenoxy)methyl]pyrrolidinehydrochloride (CAS 1219979-47-1)
- 1-(5-Bromopyridin-2-yl)cyclobutan-1-ol (CAS 1319256-44-4)
- 1-Cyclohexyl-3-(3,5-dimethylisoxazol-4-yl)-2-(2-methylquinolin-4-yl)guanidine (CAS 71079-30-6)
- N-[5-(Aminomethyl)pyridin-2-yl]propanamide (CAS 1250210-66-2)
- 3-(3,6-Diethylpyrazin-2-yl)prop-2-yn-1-ol (CAS 109191-89-1)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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