Enzalutamide Impurity 35 CAS 888072-96-6
| CAS No. | 888072-96-6 |
| Molecular Formula | C9H4F3N3 |
| Molecular Weight | 211.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Enzalutamide Impurity 35 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Enzalutamide Impurity 35 (CAS 888072-96-6), a pharmacopoeial impurity reference standard (molecular formula C9H4F3N3, MW 211.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Enzalutamide Impurity 35 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H4F3N3 |
| Molecular Weight | 211.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Enzalutamide Standards
- Enzalutamide Impurity 23 (CAS 1187368-66-6)
- Enzalutamide Impurity 33 (CAS 934600-95-0)
- Enzalutamide Impurity 30 (CAS 112704-79-7)
- Enzalutamide Impurity 36 (CAS 208122-06-9)
- Enzalutamide Impurity 22 (CAS 392-09-6)
- Enzalutamide Impurity 64 (CAS CATO-C4X-101664)
- Enzalutamide Impurity 39 (CAS CATO-C4X-101639)
- Enzalutamide Impurity 40 (CAS 3079438-61-9)
Recommended Standards
- 6-(Trifluoromethyl)-1H-indazole-3-carbonitrile (CAS 887577-45-9)
- (2E)-3-(4-fluoro-2-nitrophenyl)prop-2-enoic acid (CAS 1214790-47-2)
- 4-Amino-5-(trifluoromethyl)isophthalonitrile (CAS 2442597-62-6)
- (S)-2-Amino-6-phosphonohexanoic acid (CAS 126253-57-4)
- Sofosbuvir Impurity 8 (CAS 1910099-11-4)
- Dotinurad Impurity 34 (CAS CATO-C4X-249434)
- Terbutaline Impurity 18 (CAS CATO-C4X-118318)
- Methyl 1H-indol-5-ylcarbamate (CAS 470454-96-7)
- 4,4-Difluoro-1-(3-methoxyphenyl)-N,N-dimethylcyclohexan-1-amine (CAS 2306262-98-4)
- [1,2,4]triazolo[4,3-c]pyrimidin-3-amine (CAS 859765-68-7)
- Etomidate Impurity 16 (CAS CATO-C4X-188416)
- 4-Bromo-2h-[1,2'-bipyridin]-2-one (CAS 1823322-42-4)
- trans-((tert-Butyldimethylsilyl)oxy)cyclobutan-1-amine (CAS 2673410-97-2)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
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