Terbutaline Impurity 18 CAS CATO-C4X-118318
| CAS No. | CATO-C4X-118318 |
| Molecular Formula | C8H7BrO3 |
| Molecular Weight | 231.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Terbutaline Impurity 18.
As a process- or degradation-related impurity, Terbutaline Impurity 18 (CAS CATO-C4X-118318, C8H7BrO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Terbutaline Impurity 18 (C8H7BrO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 231.04 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7BrO3 |
| Molecular Weight | 231.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Terbutaline Standards
- Terbutaline Impurity 17 (CAS CATO-C4X-118317)
- Terbutaline Impurity 38 (CAS 62932-92-7)
- Terbutaline Impurity 66 (CAS 29415-97-2)
- Terbutaline-d9 (CAS 1189658-09-0)
- Terbutaline Impurity 41 (CAS CATO-C4X-118341)
- Terbutaline Impurity 51 (CAS 34068-01-4)
- Terbutaline impurity 124 (CAS CATO-C4X-1183124)
- Terbutaline impurity 125 (CAS CATO-C4X-1183125)
Recommended Standards
- 2-Bromo-5-methoxybenzoic Acid (CAS 22921-68-2)
- Netupitant Impurity 9 (CAS 67902-00-5)
- Di-beta,beta'-Chloroethylphosphoric Acid-d8 (CAS 1477495-02-5)
- Methyl 4-Bromosalicylate (CAS 22717-56-2)
- Vonoprazan Impurity 220 (CAS CATO-C4X-1020220)
- Vazegepant Impurity 17 (CAS CATO-C4X-320017)
- Voriconazole Impurity 43 (CAS 154335-57-6)
- (E)-1,3-Dimethyl-2-(2-(thiophen-2-yl)vinyl)-2,3-dihydro-1H-imidazole (CAS 791586-11-3)
- 100058-36-4 3-(4-Ethylphenyl)tetrahydrofuran C12H16O Y6757 (CAS 100058-36-4)
- (3Z)-3-[(Thiophen-2-yl)methylidene]piperazine-2,5-dione (CAS 338416-12-9)
- Amorolfine Impurity 43 (CAS CATO-C4X-154243)
- Methyl 5-bromo-4-nitro-1H-indazole-3-carboxylate (CAS 1403767-11-2)
- (4-(Difluoromethyl)-2-iodo-6-(trifluoromethoxy)pyridin-3-yl)methanol (CAS 1804743-97-2)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
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