Methyl 2-(5-chloro-2-(methylthio)pyrimidine-4-carboxamido)benzoate CAS 889304-30-7
| CAS No. | 889304-30-7 |
| Molecular Formula | C14H12ClN3O3S |
| Molecular Weight | 337.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(5-chloro-2-(methylthio)pyrimidine-4-carboxamido)benzoate.
CATO supplies Methyl 2-(5-chloro-2-(methylthio)pyrimidine-4-carboxamido)benzoate (CAS 889304-30-7), a certified reference material (molecular formula C14H12ClN3O3S, MW 337.78 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2-(5-chloro-2-(methylthio)pyrimidine-4-carboxamido)benzoate (C14H12ClN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-(5-chloro-2-(methylthio)pyrimidine-4-carboxamido)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN3O3S |
| Molecular Weight | 337.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-Chloro-5-(4-fluorophenyl)-7-(m-tolyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1228504-12-8)
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- N-(5-Chloro-4-methylbenzo[d]thiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide (CAS 897759-64-7)
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- N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide (CAS 897618-13-2)
- 2-Chloro-6-fluoro-N-(furan-2-ylmethyl)-N-(tetrahydro-2H-pyran-4-yl)benzamide (CAS 1448134-84-6)
- 3-((3-Chloro-4-fluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one (CAS 763119-57-9)
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Recommended Standards
- Fenquizone (CAS 20287-37-0)
- 3-(4-(n-(2-Chlorophenyl)sulfamoyl)phenyl)acrylic acid (CAS 379729-51-8)
- 2-Methoxy-4-(1-oxoisoindolin-2-yl)benzene-1-sulfonyl chloride (CAS 277758-53-9)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-5-chloro-2-(methylthio)pyrimidine-4-carboxamide (CAS 835887-67-7)
- 4-(Piperazinocarbonylmethyl)-1-bromobenzene (CAS 954582-52-6)
- 1-(2-Hydroxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethanone (CAS 130064-21-0)
- 4-(((Benzyloxy)carbonyl)amino)-3-fluorobenzoic acid (CAS 1339822-79-5)
- 5-(Trifluoromethyl)oxazolo[4,5-b]pyridin-2(3H)-one (CAS 1092569-13-5)
- tert-Butyl 3-[(4-phenylbutan-2-yl)amino]propanoate (CAS 1221341-33-8)
- Lupeol acetate (CAS 1617-68-1)
- 5-(4-Chlorophenyl)-1,3,4-thiadiazole-2-carboxylic acid (CAS 1388054-06-5)
- 4-Acetyl-N-((tetrahydrofuran-2-yl)methyl)-1H-pyrrole-2-carboxamide (CAS 439120-89-5)
- 3,6-Dichloro-4-ethynylpyridazine (CAS 2228894-69-5)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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