2-Chloro-5H-pyrrolo[2,3-b]pyrazine CAS 889447-19-2
| CAS No. | 889447-19-2 |
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 153.57 g/mol gives 2-Chloro-5H-pyrrolo[2,3-b]pyrazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-5H-pyrrolo[2,3-b]pyrazine (CAS 889447-19-2) is a high-purity analytical reference standard with the molecular formula C6H4ClN3 and a molecular weight of 153.57 g/mol.
Based on its molecular formula C6H4ClN3, 2-Chloro-5H-pyrrolo[2,3-b]pyrazine contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 153.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5H-pyrrolo[2,3-b]pyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-7H-pyrrolo[2,3-d]pyrimidine (CAS 1041864-02-1)
- 2-Chloro-1H-imidazo[4,5-b]pyridine (CAS 104685-82-7)
- 6-Chloro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1048913-70-7)
- 3-chloro-[1,2,3]triazolo[1,5-a]pyridine (CAS 1087206-32-3)
- 3-Chloro-5H-pyrrolo[2,3-b]pyrazine (CAS 1111638-10-8)
- 2-Chloro-5H-pyrrolo[3,2-d]pyrimidine (CAS 1119280-66-8)
- 1-Chloro-4-cyanatobenzene (CAS 1124-59-0)
- 5-Chloro-4-methylpyrimidine-2-carbonitrile (CAS 114969-79-8)
Recommended Standards
- 2-Chloro-4-hydroxybenzonitrile (CAS 3336-16-1)
- 2-Chloro-5-methylpyrimidine-4-carbonitrile (CAS 2751647-61-5)
- 2-Chloro-3-hydroxybenzonitrile (CAS 51786-11-9)
- 2-Chloro-6-hydroxybenzonitrile (CAS 89999-90-6)
- 1-(4-Chloro-5-isobutylthiophen-2-yl)ethanone (CAS 1399661-28-9)
- 3-Ethoxy-1H-isoindole (CAS 49619-49-0)
- 2-Ethyl-[1,3,4]oxadiazole (CAS 13148-61-3)
- 2-(Methylsulfonyl)-5-(trifluoromethyl)aniline (CAS 402-19-7)
- 2,5-Furandione, polymer with ethenylbenzene, potassium salt (CAS 26602-04-0)
- (3S,4R)-tert-Butyl 3-ethynyl-4-hydroxypyrrolidine-1-carboxylate (CAS 1932625-88-1)
- Europate(1-),[[N,N',N'',N'''-[(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κN1,κN4,κN7,κN10)bis[1-(oxo-κO)-2,1-ethanediyl]]tetrakis[glycinato]](4-)]-, hydrogen (CAS 481668-57-9)
- Zinc, [[α,α'-(o-phenylenedinitrilo)di-o-cresolato](2-)]- (CAS 21380-07-4)
- 2-Acetamido-3-(thiophen-3-yl)propanoic acid (CAS 67206-08-0)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
Why CATO?
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