5-Methyl-2-(pyridin-4-yl)thiazole-4-carboxylic acid CAS 889940-62-9

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-Methyl-2-(pyridin-4-yl)thiazole-4-carboxylic acid (CAS 889940-62-9), molecular formula C10H8N2O2S and molecular weight 220.25 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C10H8N2O2S, 5-Methyl-2-(pyridin-4-yl)thiazole-4-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 220.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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