5-Chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylic acid CAS 890587-32-3
| CAS No. | 890587-32-3 |
| Molecular Formula | C7H7ClN2O4S |
| Molecular Weight | 250.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylic acid is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylic acid (CAS 890587-32-3), a certified reference material (molecular formula C7H7ClN2O4S, MW 250.66 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-2-(ethylsulfonyl)pyrimidine-4-carboxylic acid (C7H7ClN2O4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O4S |
| Molecular Weight | 250.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- Methyl 2-Chloro-5-sulfamoylnicotinate (CAS 1118787-24-8)
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Recommended Standards
- 5-Amino-1-(4-chloro-2-fluorophenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2197063-20-8)
- 5-chloro-2-methyl-4-nitrobenzene-1-sulfonamide (CAS 23454-13-9)
- 5-(Chlorosulfonyl)-2-hydroxy-4-methylbenzoic acid (CAS 926270-90-8)
- Methyl 5-(chlorosulfonyl)-2-hydroxybenzoate (CAS 60638-81-5)
- 4-Fluoro-3-(hydroxymethyl)benzonitrile (CAS 856931-47-0)
- 7-(Trifluoromethoxy)-1H-benzo[d]imidazole-2-carbaldehyde (CAS 1805836-68-3)
- 1-(3-Cyanophenyl)-3-isopropyl-1h-pyrazole-5-carboxylic acid (CAS 1012879-75-2)
- 1-(2-Chloroacetyl)-2,2,5,5-tetramethylimidazolidin-4-one (CAS 209336-83-4)
- 4-(4-Methyl-1,3-thiazol-2-yl)benzaldehyde (CAS 1082943-06-3)
- 4-(1,3-Dioxolan-2-ylmethyl)biphenyl (CAS 898759-54-1)
- 4-(Pyridin-2-ylmethoxy)phenylboronic acid (CAS 1228180-82-2)
- 1-(3-Bromophenyl)-4-hydrazinyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416348-32-7)
- (1S,2S)-N-Methyl-2-(pyrrolidin-1-yl)cyclohexanamine (CAS 67198-53-2)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
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