(2R,3S,5R)-5-(6-Amino-2-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol CAS 89178-21-2
| CAS No. | 89178-21-2 |
| Molecular Formula | C10H12BrN5O3 |
| Molecular Weight | 330.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 330.14 g/mol gives (2R,3S,5R)-5-(6-Amino-2-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (2R,3S,5R)-5-(6-Amino-2-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 89178-21-2), a certified reference material (molecular formula C10H12BrN5O3, MW 330.14 g/mol) for analytical method development and quality control.
The molecular framework of (2R,3S,5R)-5-(6-Amino-2-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (C10H12BrN5O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2R,3S,5R)-5-(6-Amino-2-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12BrN5O3 |
| Molecular Weight | 330.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- 8-Bromo-2'-deoxyadenosine (CAS 14985-44-5)
- 2,2-Dichloro-N-(4-(4-fluorophenyl)-6-methoxypyrimidin-2-yl)acetamide (CAS 648410-29-1)
- 5-Iodo-N-(pyridin-4-yl)thiophene-3-carboxamide (CAS 1311991-07-7)
- 2-Iodo-N-(thiazol-2-yl)benzamide (CAS 312756-51-7)
- 3-[(2-methoxyethyl)amino]-1λ6-thiolane-1,1-dione hydrochloride (CAS 483351-50-4)
- N-(2-(Cyclopropanecarbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)thiophene-2-carboxamide (CAS 955766-46-8)
- 3-(2,2-Dichlorovinyl)-4-methylphenol (CAS 90348-56-4)
- 2-Methoxy-5-(trifluoromethoxy)benzenesulfonyl chloride (CAS 1010422-55-5)
- Alprazolam 5,6-Epoxide (CAS 36916-14-0)
- 1-(3-Methylthiophen-2-yl)prop-2-yn-1-ol (CAS 857971-86-9)
- 2-Amino-3-(imidazo[1,2-a]pyridin-3-yl)propanoic acid (CAS 791773-83-6)
- Methyl 5-(furan-2-yl)nicotinate (CAS 93349-97-4)
- N-(3-Methyl-5-phenyl-1H-pyrazol-4-yl)thiophene-3-carboxamide (CAS 824969-20-2)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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