Alprazolam 5,6-Epoxide CAS 36916-14-0
| CAS No. | 36916-14-0 |
| Molecular Formula | C17H29ClN4O |
| Molecular Weight | 340.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Alprazolam 5,6-Epoxide.
Alprazolam 5,6-Epoxide (CAS 36916-14-0), molecular formula C17H29ClN4O and molecular weight 340.89 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Alprazolam 5,6-Epoxide (C17H29ClN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Alprazolam 5,6-Epoxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H29ClN4O |
| Molecular Weight | 340.89 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Alprazolam Standards
- Alprazolam Impurity 9 (CAS 17387-32-5)
- Alprazolam EP Impurity F (CAS 37945-07-6)
- Alprazolam impurity 21 (CAS 37945-06-5)
- Alprazolam EP Impurity B (CAS 38150-27-5)
- Alprazolam EP Impurity B (CAS CATO-C4X-146014)
- Alprazolam Impurity 8 (CAS 30896-65-2)
- Alprazolam EP Impurity D (CAS CATO-C4X-146010)
- Alprazolam Impurity 16 (CAS CATO-C4X-146016)
Recommended Standards
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- 1,3-Dichloro-4-iodo-2-(trifluoromethyl)benzene (CAS 2384307-56-4)
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- 2H-Indazole-2-acetic acid (CAS 58037-05-1)
- 2-(Cyclopropylmethyl)-4-isopropylphenol (CAS 1243280-52-5)
- tert-Butyl (1-(4-(pyridin-2-yl)piperazin-1-yl)propan-2-yl)carbamate (CAS 1215003-26-1)
- 2-(5-Bromopyridin-3-yl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid (CAS 1363405-83-7)
- rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl formate (CAS 1200-67-5)
- 2-((Piperidin-3-yloxy)methyl)pyridine (CAS 933716-44-0)
- Semaglutide Sodium Salt (CAS CATO-C4X-222620)
Why CATO?
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