4-Chloro-N-((1,3-diphenyl-1H-pyrazol-5-yl)methylene)aniline CAS 89185-69-3
| CAS No. | 89185-69-3 |
| Molecular Formula | C22H16ClN3 |
| Molecular Weight | 357.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-N-((1,3-diphenyl-1H-pyrazol-5-yl)methylene)aniline (CAS 89185-69-3), a certified reference material (molecular formula C22H16ClN3, MW 357.84 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-N-((1,3-diphenyl-1H-pyrazol-5-yl)methylene)aniline (C22H16ClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3 |
| Molecular Weight | 357.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-((5-Chloro-4-(methyl(1-methylpiperidin-4-yl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CAS 1137477-50-9)
- 4-Chloro-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 1142945-83-2)
- Methyl 2-chloro-4-{4-[(piperidin-1-yl)carbonyl]phenyl}benzoate (CAS 1820712-06-8)
- (2E)-3-(2-Chloro-6-fluorophenyl)-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)prop-2-en-1-one (CAS 477847-71-5)
- 4-Chloro-N-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)benzamide (CAS 320420-17-5)
- 2-Chloro-4-methyl-3-(4-methylbenzenesulfonyl)-6-phenylpyridine (CAS 339017-13-9)
- 3-Chloro-α-[(4-methylphenyl)sulfonyl]-2-quinoxalineacetonitrile (CAS 121512-59-2)
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Recommended Standards
- 4-[5-(4-Chlorobenzenesulfinyl)-1,2,3-thiadiazole-4-carbonyl]morpholine (CAS 306976-93-2)
- tert-Butyl 4-(((6-amino-5-chloropyrimidin-4-yl)amino)methyl)-3-hydroxypiperidine-1-carboxylate (CAS 2007910-42-9)
- (S)-C33 (CAS 2066488-39-7)
- Yttrium(III) carbonate (CAS 556-28-5)
- 2-(4-Benzylphenoxy)-5-fluoroaniline (CAS 946729-55-1)
- 7-(Trifluoromethyl)imidazo[1,2-a]pyrimidine-6-carboxylic acid (CAS 1260847-63-9)
- 4-CHloro-2-nitro-3-(trifluoromethyl)phenol (CAS 1192021-50-3)
- 2-Iodo-5-methylpyrimidine (CAS 154129-30-3)
- 3-amino-N-[4-(2-methoxyethoxy)butyl]benzene-1-sulfonamide (CAS 1707958-47-1)
- 2-(3-chloro-2-fluorophenyl)acetaldehyde (CAS 1256479-71-6)
- 2-(4-Fluoro-1H-indol-3-yl)acetamide (CAS 345264-93-9)
- 3-(Propan-2-yl)-1,2-oxazole-5-carbaldehyde (CAS 121604-54-4)
- N-[(1S,2S)-2-Aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea (CAS 1027476-96-5)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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