7-Chloro-N-(3,4-dimethylphenyl)-3-((3,4-dimethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine CAS 893788-57-3
| CAS No. | 893788-57-3 |
| Molecular Formula | C25H22ClN5O2S |
| Molecular Weight | 491.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
7-Chloro-N-(3,4-dimethylphenyl)-3-((3,4-dimethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 893788-57-3) is a high-purity analytical reference standard with the molecular formula C25H22ClN5O2S and a molecular weight of 491.99 g/mol.
The molecular framework of 7-Chloro-N-(3,4-dimethylphenyl)-3-((3,4-dimethylphenyl)sulfonyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (C25H22ClN5O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H22ClN5O2S |
| Molecular Weight | 491.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 7-Chloro-3-(3,4-dimethylbenzenesulfonyl)-N-(3,5-dimethylphenyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 893788-59-5)
- 6-Chloro-N-(2,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole-2-carboxamide (CAS 1031540-29-0)
- N-(5-chloro-2-methylphenyl)-2-((5-(((2,6-dimethylphenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332911-63-4)
- 2-((2-Chloro-6-fluorobenzyl)thio)-6,7-dimethoxy-3-octylquinazolin-4(3H)-imine (CAS 860789-55-5)
- 5-[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)sulphonyl]-4-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 255872-73-2)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-(N,N-dimethylsulfamoyl)phenyl)piperazine-1-carboxamide (CAS 692733-09-8)
- 4-Chloro-N-(2-(2-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)butanoyl)hydrazinyl)-2-oxoethyl)benzamide (CAS 338409-93-1)
- N'-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[(2,6-dichlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carbohydrazide (CAS 338978-39-5)
Recommended Standards
- N-(4-Acetamidophenyl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477332-94-8)
- 3-Benzyl-5-((4-chlorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 477768-30-2)
- Birabresib (CAS 202590-98-5)
- 2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide (CAS 1983196-25-3)
- 4-(4-Ethoxyphenyl)-1-(prop-2-yn-1-yl)-1H-pyrazole (CAS 1394023-21-2)
- 2-Chloro-1-(quinolin-8-yl)ethanone (CAS 129486-81-3)
- Ethyl 2-bromo-5-cyano-3-hydroxybenzoate (CAS 1807079-45-3)
- 1H-Pyrazolo[3,4-d]pyrimidine-1-propanenitrile, 6-chloro-α,α,β-trimethyl- (CAS 2839521-74-1)
- 4-Methylindoline (CAS 62108-16-1)
- N-(2-Phenoxyethyl)-4-(trifluoromethyl)benzamide (CAS 879184-79-9)
- Allyl(3-chloro-4-fluorophenyl)sulfane (CAS 1378324-63-0)
- 1-(1-Methylbenzo[f]quinazolin-3-yl)guanidine hydrochloride (CAS 1150-41-0)
- 2-(3-Chlorophenyl)-5-((2,6-dimethylmorpholino)methyl)benzo[d]oxazole (CAS 1706453-04-4)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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