2-{[4-(2-Chlorobenzoyl)piperazin-1-yl]carbonyl}benzoic acid CAS 896508-49-9
| CAS No. | 896508-49-9 |
| Molecular Formula | C19H17ClN2O4 |
| Molecular Weight | 372.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-{[4-(2-Chlorobenzoyl)piperazin-1-yl]carbonyl}benzoic acid (CAS 896508-49-9), molecular formula C19H17ClN2O4 and molecular weight 372.80 g/mol, is a CATO reference standard with documented purity and traceability.
2-{[4-(2-Chlorobenzoyl)piperazin-1-yl]carbonyl}benzoic acid (C19H17ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H17ClN2O4 |
| Molecular Weight | 372.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- N-(4-Chlorobenzoyl)-2-(2,4-dichlorophenoxy)ethanehydrazonamide (CAS 338395-78-1)
- N-(4-Chlorobenzoyl)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetohydrazide (CAS 339105-83-8)
- 1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester (CAS 1568-35-0)
- 1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester (CAS 1568-36-1)
- 339010-20-7 4-{[(4-chlorobenzoyl)oxy]imino}-1-(4-nitrophenyl)piperidine KS-00003CG1 (CAS 339010-20-7)
- N-(2-(2-chlorobenzoyl)-3-oxo-2,3-dihydro-1,2,4-thiadiazol-5-yl)-4-methylbenzamide (CAS 478031-94-6)
- 4-({[(4-chlorobenzoyl)amino]carbonyl}amino)-3-fluorobenzene-1-sulphonyl fluoride (CAS 284674-50-6)
- 4-(4-Chlorobenzoyl)-N'-(6-chloropyridin-2-yl)-1H-pyrrole-2-carbohydrazide (CAS 338403-50-2)
Recommended Standards
- 1365961-74-5 2-Chloro-N-(2,5-dioxo-1-phenylpyrrolidin-3-yl)-N-(2-methoxyphenyl)acetamide MFCD22056654 (CAS 1365961-74-5)
- 3-(2-Chlorophenyl)-5-methyl-N-(2-phenoxyethoxy)-1,2-oxazole-4-carboxamide (CAS 338406-47-6)
- (S)-Methyl 2-(5-(4-chlorophenyl)-7-methoxy-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)acetate (CAS 1300019-46-8)
- 4-Ethoxy-3-(3-(4-fluorophenyl)ureido)benzene-1-sulfonyl chloride (CAS 678186-02-2)
- 4-Chloro-n,n-diethylbutanamide (CAS 56794-28-6)
- 2-Amino-9-(4-hydroxy-3-(hydroxymethyl)but-2-en-1-yl)-1H-purin-6(9H)-one (CAS 99776-28-0)
- 8-Bromo-1-chloroisoquinoline (CAS 1233025-78-9)
- Methyl 3-(3,5-difluorophenoxy)-2-hydroxy-2-methylpropanoate (CAS 1480951-74-3)
- rel-Potassium sodium (2R,3R)-2,3-dihydroxysuccinate (CAS 147-79-5)
- 1-(7-(2-Chlorophenyl)-1,4-thiazepan-4-yl)-2-(cyclopentylthio)ethan-1-one (CAS 1795302-31-6)
- Olanzapine Impurity 20 (CAS 1017241-34-7)
- (<I>S</I>)-(-)-4-isopropyl-5,5-dimethyl-2-oxazolidinone (CAS 168297-86-7)
- tert-Butyl 3-(2,3-dimethoxyphenyl)piperazine-1-carboxylate (CAS 886769-39-7)
- Insulin degludec (CAS 844439-96-9)
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