1-(4-Chlorophenyl)isoquinolin-3(2H)-one CAS 89721-06-2
| CAS No. | 89721-06-2 |
| Molecular Formula | C15H10ClNO |
| Molecular Weight | 255.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Chlorophenyl)isoquinolin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(4-Chlorophenyl)isoquinolin-3(2H)-one (CAS 89721-06-2) is a high-purity analytical reference standard with the molecular formula C15H10ClNO and a molecular weight of 255.70 g/mol.
The molecular framework of 1-(4-Chlorophenyl)isoquinolin-3(2H)-one (C15H10ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H10ClNO |
| Molecular Weight | 255.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- EThyl 3-[(3-chlorophenyl)formamido]propanoate (CAS 1116115-90-2)
- 5-(4-Chlorophenyl)-3-phenylisoxazole (CAS 1148-87-4)
- (4-Chlorophenyl)(4,4-dihydroxypiperidin-1-yl)methanone (CAS 1161771-90-9)
- 3-(2-Chlorophenyl)-5-phenyl-1H-1,2,4-triazole (CAS 118863-81-3)
- 2-(4-Chlorophenyl)-1H-indole-3-carbaldehyde (CAS 1217-83-0)
- 3-(4-Chlorophenyl)isoquinolin-1(2H)-one (CAS 124394-22-5)
- 2-(1-(4-Chlorophenyl)-1H-pyrazol-5-yl)pyridine (CAS 1269291-42-0)
- 2-(1-(3-Chlorophenyl)-1H-pyrazol-5-yl)pyridine (CAS 1269291-80-6)
Recommended Standards
- 1-(4-Chlorophenyl)-4-methyl-4-nitropentan-1-one (CAS 400085-21-4)
- 1-(5-Chloro-6-methylpyrazin-2-yl)piperidine-4-carboxylic acid (CAS 919536-39-3)
- 1-(4-Chloro-2-nitrophenyl)-4-methylpiperazine (CAS 65639-68-1)
- 1-(6-Chloropyridazin-3-yl)piperidine-4-carbohydrazide (CAS 338413-80-2)
- 2-Hydroxy-4-methoxybenzaldehyde (CAS 673-22-3)
- (2,4-Dimethylphenyl)hydrazine (CAS 615-00-9)
- 4-Methyl-6-(propylsulfonyl)quinolin-2(1H)-one (CAS 1207858-39-6)
- Thiadiazin (CAS 3773-49-7)
- 5-Cyclopropoxy-4-methoxypicolinic acid (CAS 1243395-57-4)
- Methyl 1-phenyl-1H-benzo[d]imidazole-5-carboxylate (CAS 220495-70-5)
- (4,4-Dimethylazetidin-2-yl)methanol (CAS 1408242-58-9)
- 2-(pyrrolidin-3-yloxy)pyridine (CAS 253603-61-1)
- 3-(4-Chlorophenyl)cyclopentan-1-one (CAS 115169-77-2)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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