(2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone CAS 898756-27-9
| CAS No. | 898756-27-9 |
| Molecular Formula | C22H22F3NO3 |
| Molecular Weight | 405.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (CAS 898756-27-9) is a high-purity analytical reference standard with the molecular formula C22H22F3NO3 and a molecular weight of 405.41 g/mol.
Structurally, (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (C22H22F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 405.41 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H22F3NO3 |
| Molecular Weight | 405.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-(trifluoromethyl)phenyl)methanone (CAS 898756-30-4)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-(trifluoromethyl)phenyl)methanone (CAS 898756-33-7)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (CAS 898762-03-3)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-(trifluoromethyl)phenyl)methanone (CAS 898762-05-5)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-(trifluoromethyl)phenyl)methanone (CAS 898762-07-7)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (CAS 898758-10-6)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-(trifluoromethyl)phenyl)methanone (CAS 898758-12-8)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-(trifluoromethyl)phenyl)methanone (CAS 898758-14-0)
Recommended Standards
- ((3aR,4R,6R,6aR)-2,2-Dimethyl-6-(2-oxo-4-(1H-1,2,4-triazol-1-yl)pyrimidin-1(2H)-yl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate (CAS 2346620-54-8)
- Methyl 2-((7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl)amino)nicotinate (CAS 1956371-58-6)
- N-(4-(1-(2-(4,5-Dihydro-1H-imidazol-2-yl)hydrazono)ethyl)phenyl)-7-nitro-1H-indole-2-carboxamide (CAS 1093793-10-2)
- Taltirelin (CAS 103300-74-9)
- Magnesium Potassium Aspartate (CAS 8076-65-1)
- (4-amino-2,2,3-trimethylcyclohexyl)methanol (CAS 1053170-08-3)
- N-(4-((4-methoxyphenyl)amino)-4-oxobutyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 956200-42-3)
- 4-(2-Aminoethyl)-N,N-dimethylaniline hydrochloride (CAS 2048273-78-3)
- 3-((2-(Isoquinolin-6-ylamino)-2-oxoethyl)amino)-N-phenylbenzamide (CAS 920513-52-6)
- 2,3-Dihydro-1-hydroxy-1H-indene-1-carboxylic Acid Methyl Ester (CAS 901773-92-0)
- 7-Chloro-5-methylindoline (CAS 176097-90-8)
- 3-(Bromomethyl)-4-methyl-1,2-oxazole (CAS 952195-21-0)
- 7-Methoxy-N-(3-methylisothiazol-5-yl)benzofuran-2-carboxamide (CAS 1219911-58-6)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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