(2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone CAS 898756-48-4
| CAS No. | 898756-48-4 |
| Molecular Formula | C21H21Cl2NO3 |
| Molecular Weight | 406.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone (CAS 898756-48-4), molecular formula C21H21Cl2NO3 and molecular weight 406.30 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H21Cl2NO3, (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 406.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21Cl2NO3 |
| Molecular Weight | 406.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,4-dichlorophenyl)methanone (CAS 898756-51-9)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,5-dichlorophenyl)methanone (CAS 898756-54-2)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,4-dichlorophenyl)methanone (CAS 898756-57-5)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,5-dichlorophenyl)methanone (CAS 898756-60-0)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,3-dichlorophenyl)methanone (CAS 898762-19-1)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,4-dichlorophenyl)methanone (CAS 898762-22-6)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2,5-dichlorophenyl)methanone (CAS 898762-25-9)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3,4-dichlorophenyl)methanone (CAS 898762-28-2)
Recommended Standards
- N-(2-Aminobenzo[d]thiazol-6-yl)-2-(2-bromo-4,6-dimethylphenoxy)acetamide (CAS 1706450-90-9)
- Lesinurad Impurity 3 (CAS 1533519-96-8)
- tert-Butyl 4-(3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine-1-carboxylate (CAS 1129541-83-8)
- Arbidol Impurity 56 (CAS CATO-C4X-112956)
- 2-Bromo-4-cyclopropoxybenzoic acid (CAS 1243345-00-7)
- (1R,4r)-4-(methoxymethyl)cyclohexan-1-amine (CAS 919799-82-9)
- (4,5-Dimethoxy-2-nitrophenyl)(5-methylfuran-2-yl)methanone (CAS 676546-91-1)
- 6-Chloro-1',2',3',6'-tetrahydro-2,4'-bipyridine (CAS 209159-44-4)
- 2-(4-(3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 1251625-52-1)
- Benzyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate (CAS 1428727-74-5)
- 1-Chloro-2-ethoxy-3-fluoro-5-nitrobenzene (CAS 1881331-85-6)
- 3-((3-Formylphenoxy)methyl)-4-methoxybenzaldehyde (CAS 438218-17-8)
- Ligagliptin impurity 106 (CAS CATO-C4X-1101106)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
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