(4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone CAS 898757-76-1
| CAS No. | 898757-76-1 |
| Molecular Formula | C21H22BrNO3 |
| Molecular Weight | 416.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone (CAS 898757-76-1), a certified reference material (molecular formula C21H22BrNO3, MW 416.31 g/mol) for analytical method development and quality control.
The molecular framework of (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone (C21H22BrNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22BrNO3 |
| Molecular Weight | 416.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone (CAS 898755-97-0)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-bromophenyl)methanone (CAS 898755-99-2)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-bromophenyl)methanone (CAS 898761-69-8)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-bromophenyl)methanone (CAS 898761-71-2)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-bromophenyl)methanone (CAS 898757-78-3)
- Ethyl 8-(2-((1,4-dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)-8-oxooctanoate (CAS 898781-35-6)
- Ethyl 8-(3-((1,4-dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)-8-oxooctanoate (CAS 898762-68-0)
- Ethyl 8-(4-((1,4-dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)-8-oxooctanoate (CAS 898782-16-6)
Recommended Standards
- Methyl 8-bromo-1-(4-methoxybenzyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxylate (CAS 497224-08-5)
- Rosuvastatin Impurity 226 (CAS CATO-C4X-1169226)
- Rosuvastatin Impurity 228 (CAS CATO-C4X-1169228)
- (S)-3-(4-(4-bromobutoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1579942-12-3)
- Methyl 5-amino-1H-benzo[d]imidazole-6-carboxylate (CAS 181284-95-7)
- 1-(3-((4-(Thiophen-3-yl)piperidin-1-yl)sulfonyl)phenyl)ethan-1-one (CAS 1448071-51-9)
- 5-amino-1-(3-bromophenyl)-1H-pyrazole-4-carbonitrile (CAS 71856-56-9)
- 1-Methyl-2-piperidin-1-ylmethyl-1H-benzoimidazol-5-ylamine trihydrochloride (CAS 1158191-61-7)
- 7-Amino-1,3-naphthalenedisulfonic acid monopotassium salt monohydrate (CAS 303137-06-6)
- 2-(Isoquinolin-1-ylmethylene)hydrazinecarbothioamide (CAS 2365-26-6)
- Letrozole Impurity 38 (CAS 874-86-2)
- (2-Isobutoxy-5-methylphenyl)(methyl)sulfane (CAS 1379322-55-0)
- 4-(Aminomethyl)-2-hydroxybenzenesulfonamide (CAS 1243414-38-1)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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