(3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone CAS 898761-75-6
| CAS No. | 898761-75-6 |
| Molecular Formula | C21H22ClNO3 |
| Molecular Weight | 371.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone (CAS 898761-75-6), a certified reference material (molecular formula C21H22ClNO3, MW 371.86 g/mol) for analytical method development and quality control.
The molecular framework of (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone (C21H22ClNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22ClNO3 |
| Molecular Weight | 371.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dioxa Standards
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-chlorophenyl)methanone (CAS 898756-22-4)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-chlorophenyl)methanone (CAS 898756-00-8)
- (2-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone (CAS 898756-02-0)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-chlorophenyl)methanone (CAS 898761-99-4)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-chlorophenyl)methanone (CAS 898761-73-4)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-chlorophenyl)methanone (CAS 898758-06-0)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(3-chlorophenyl)methanone (CAS 898757-80-7)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(4-chlorophenyl)methanone (CAS 898757-82-9)
Recommended Standards
- (R)-(9H-Fluoren-9-yl)methyl (1-chloro-4-methyl-1-oxopentan-2-yl)carbamate (CAS 198544-60-4)
- 1-[5-(4-Chlorobenzenesulfonyl)-1,2,3-thiadiazole-4-carbonyl]piperidine (CAS 306977-06-0)
- Trazodone EP Impurity C (CAS 157072-19-0)
- 1-[6-(4-Chlorophenoxy)hexyl]-3-cyano-2-pyridin-4-ylguanidine (CAS 200484-11-3)
- Methyl 5-(2-fluorophenyl)-2-imino-2,3-dihydrothiazole-4-carboxylate (CAS 886361-38-2)
- 5-Chloro-3-{[(2-methylphenyl)methyl]sulfanyl}-1,2,4-thiadiazole (CAS 1326814-53-2)
- 4-Cyclopropoxy-2-isopropoxy-1-isopropylbenzene (CAS 1243410-58-3)
- Cycloheptylmethanesulfonamide (CAS 1496157-02-8)
- 3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carbonitrile (CAS 1314979-27-5)
- Cetirizine Impurity 59 (Mixture of Isomers) (CAS CATO-C4X-108359)
- 3-(4-Bromophenoxy)propan-1-amine (CAS 933717-18-1)
- Potassium trifluoro(2-methylprop-1-en-1-yl)borate (CAS 1134643-87-0)
- 2-Amino-4-phenyl-4H-benzo[g]chromene-3-carbonitrile (CAS 924708-55-4)
- Neuropeptide W-23 (rat) (CAS 383415-89-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com