1-(4-Bromo-2-fluorophenyl)-3-(4-bromophenyl)propan-1-one CAS 898761-78-9
| CAS No. | 898761-78-9 |
| Molecular Formula | C15H11Br2FO |
| Molecular Weight | 386.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Bromo-2-fluorophenyl)-3-(4-bromophenyl)propan-1-one (CAS 898761-78-9) is a high-purity analytical reference standard with the molecular formula C15H11Br2FO and a molecular weight of 386.05 g/mol.
The molecular framework of 1-(4-Bromo-2-fluorophenyl)-3-(4-bromophenyl)propan-1-one (C15H11Br2FO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-Bromo-2-fluorophenyl)-3-(4-bromophenyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11Br2FO |
| Molecular Weight | 386.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-(4-Bromo-3-fluorophenyl)-3-(3-bromophenyl)propan-1-one (CAS 898760-36-6)
- 4-Bromo-3-(3-bromophenyl)-2-fluoropropiophenone (CAS 898760-59-3)
- 4-Bromo-3-(4-bromophenyl)-3-fluoropropiophenone (CAS 898761-61-0)
- 5-Bromo-2-((3-bromobenzyl)oxy)benzoic acid (CAS 1039982-37-0)
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