3-Chloro-4-fluoro-3-(2-methylphenyl)propiophenone CAS 898789-66-7
| CAS No. | 898789-66-7 |
| Molecular Formula | C16H14ClFO |
| Molecular Weight | 276.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Chloro-4-fluoro-3-(2-methylphenyl)propiophenone (CAS 898789-66-7), molecular formula C16H14ClFO and molecular weight 276.73 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-4-fluoro-3-(2-methylphenyl)propiophenone (C16H14ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 3-Chloro-4-fluoro-3-(2-methylphenyl)propiophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClFO |
| Molecular Weight | 276.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-(2-Chloro-4-fluorophenyl)-3-(o-tolyl)propan-1-one (CAS 898789-85-0)
- 1-(3-Chloro-4-fluorophenyl)-3-(m-tolyl)propan-1-one (CAS 898790-93-7)
- 1-(4-Chloro-3-fluorophenyl)-3-(m-tolyl)propan-1-one (CAS 898790-90-4)
- 1-(4-Chloro-3-fluorophenyl)-3-(p-tolyl)propan-1-one (CAS 898768-91-7)
- 2-Chloro-4-fluoro-3-(3-methylphenyl)propiophenone (CAS 898791-14-5)
- 3-(3-Chloro-5-fluorophenyl)-1-(m-tolyl)propan-1-one (CAS 898750-07-7)
- 3-(3-Chloro-5-fluorophenyl)-1-(p-tolyl)propan-1-one (CAS 898750-10-2)
- 3-Chloro-4-fluoro-3-(4-methylphenyl)propiophenone (CAS 898768-93-9)
Recommended Standards
- 3-Chloro-5-fluoro-3-(2-methylphenyl)propiophenone (CAS 898789-88-3)
- 3-Chloro-5-fluoro-3-(3-methylphenyl)propiophenone (CAS 898791-17-8)
- 3-Chloro-5-fluoro-3-(4-methylphenyl)propiophenone (CAS 898769-13-6)
- 4-(Chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene (CAS 957205-24-2)
- (1S,2S)-1-Amino-1-(3-fluoro-5-methoxyphenyl)propan-2-ol (CAS 1269917-71-6)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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