3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one CAS 899348-49-3
| CAS No. | 899348-49-3 |
| Molecular Formula | C17H13F2NO3S |
| Molecular Weight | 349.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (C17H13F2NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 899348-49-3), molecular formula C17H13F2NO3S and molecular weight 349.35 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13F2NO3S |
| Molecular Weight | 349.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dimethylphenyl Standards
- 3-((2,4-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1325304-15-1)
- 3-((3,4-Dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326806-71-6)
- 2-((3,4-Dimethylphenyl)amino)-2-oxoethyl 4-(1H-pyrazol-1-yl)benzoate (CAS 956964-02-6)
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- Ethyl 2-(3-{[(2,3-dimethylphenyl)carbamoyl]methyl}-4-oxo-1,3-thiazolidin-2-ylidene)acetate (CAS 565180-52-1)
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Recommended Standards
- 2-Morpholinomethyl-4-trifluoromethylbenzophenone (CAS 898750-83-9)
- 3-(4-Ethylbenzenesulfonyl)-6,7-difluoro-1,4-dihydroquinolin-4-one (CAS 902298-06-0)
- 2-[(12-Bromododecyl)oxy]tetrahydro-2H-pyran (CAS 88517-92-4)
- 3-[2-(Dimethylamino)Ethoxy]-1-[3-(Trifluoromethyl)Phenyl]-1H-Indazole (CAS 21487-12-7)
- 1-(2-Chlorophenyl)-N-isopropylmethanesulfonamide (CAS 827621-53-4)
- Z-N-Me-D-Glu(OtBu)-OH (CAS 140837-98-5)
- 5-(4,5-Dimethylthiophen-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 588685-93-2)
- (2E)-4-(3-Hydroxy-2-nitrophenyl)-4-oxo-2-butenoic Acid Methyl Ester 224044-67-1 (CAS 224044-67-1)
- tert-Butyl 3-bromo-5-fluorobenzoate (CAS 1262834-57-0)
- 3-(((3-Fluorobenzyl)oxy)methyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (CAS 1306739-12-7)
- 9-Benzyl-2-fluoro-9H-purin-6-amine (CAS 2357-25-7)
- 6-(4-Chlorobenzyl)-5-methyl-7-oxo-6,7-dihydroisothiazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1779133-21-9)
- 4-(Ethylthio)-2-phenyl-5H-pyrrolo[3,2-d]pyrimidine-7-carbaldehyde (CAS 89177-10-6)
- Tau Peptide (273-284) trifluoroacetate salt (CAS 1663490-91-2)
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