2-chloro-5-hydroxy-4-methoxybenzaldehyde CAS 89938-55-6
| CAS No. | 89938-55-6 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-chloro-5-hydroxy-4-methoxybenzaldehyde (CAS 89938-55-6), molecular formula C8H7ClO3 and molecular weight 186.59 g/mol, is a CATO reference standard with documented purity and traceability.
2-chloro-5-hydroxy-4-methoxybenzaldehyde (C8H7ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-chloro-5-hydroxy-4-methoxybenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related chloro Standards
- 4-Chloro-2-(hydroxymethyl)benzoic acid (CAS 100448-59-7)
- Methyl 2-Chloro-4-hydroxybenzoate (CAS 104253-44-3)
- 3-Chloro-2,4-dihydroxy-6-methylbenzaldehyde (CAS 106325-72-8)
- 2-Chloro-4-(hydroxymethyl)benzoic acid (CAS 1071989-48-4)
- Methyl 2-chloro-3-hydroxybenzoate (CAS 1125632-11-2)
- 2-Chloro-6-hydroxy-4-methoxybenzaldehyde (CAS 116475-68-4)
- 2-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-13-6)
- 4-Chloro-3-(hydroxymethyl)benzoic acid (CAS 1187238-15-8)
Recommended Standards
- 2-Chloro-5-(hydroxymethyl)benzoic acid (CAS 90270-93-2)
- 2-Chloro-5-methoxybenzoic Acid (CAS 6280-89-3)
- 2-Chloro-4-Methoxybenzoic Acid (CAS 21971-21-1)
- 2-Chloro-6-methoxybenzoic acid (CAS 3260-89-7)
- tert-Butyl 4-bromo-1H-indole-2-carboxylate (CAS 681288-90-4)
- 4-(1-Amino-ethyl)-benzoic acid hydrochloride (CAS 1187930-54-6)
- N-(4-Oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-2-yl)benzamide (CAS 88523-00-6)
- N-Methyl-N-(p-tolyl)quinazolin-4-amine (CAS 827030-64-8)
- Methyl 2,3-dioxoindoline-7-carboxylate (CAS 103030-10-0)
- 3-Amino-5-chloropicolinaldehyde (CAS 1289046-39-4)
- Benzyl 3',4'-dihydro-1'H-spiro[pyrrolidine-3,2'-[1,8]naphthyridine]-1-carboxylate (CAS 2715051-13-9)
- (S,4Z,6E,10Z)-8-Hydroxyhexadeca-4,6,10-trienoic acid (CAS 121842-79-3)
- 1-Bromo-3-ethynyl-2-fluorobenzene (CAS 1701568-15-1)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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