1-(Difluoromethyl)-1,2-dihydropyridin-2-one CAS 899452-34-7
| CAS No. | 899452-34-7 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Difluoromethyl)-1,2-dihydropyridin-2-one.
CATO supplies 1-(Difluoromethyl)-1,2-dihydropyridin-2-one (CAS 899452-34-7), a certified reference material (molecular formula C6H5F2NO, MW 145.11 g/mol) for analytical method development and quality control.
1-(Difluoromethyl)-1,2-dihydropyridin-2-one (C6H5F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 5-(Difluoromethyl)pyridin-3-ol (CAS 1393541-20-2)
- 5-(Difluoromethyl)-2(1H)-pyridinone 1402550-75-7 5-(Difluoromethyl)pyridin-2(1H)-one (CAS 1402550-75-7)
- 1-(difluoromethyl)-1H-pyrrole-2-carbaldehyde (CAS 1519187-90-6)
- 6-(Difluoromethyl)pyrimidin-4-amine (CAS 1706464-15-4)
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- 2-(Difluoromethyl)pyrimidin-5-amine (CAS 1781133-28-5)
- 3-(Difluoromethyl)pyrazin-2-amine (CAS 1785423-85-9)
Recommended Standards
- (S)-2-(2-Oxooxazolidin-5-yl)acetic acid (CAS 851387-87-6)
- 2-(Difluoromethoxy)pyridine (CAS 865075-07-6)
- (S)-1-Hydroxy-5-oxopyrrolidine-2-carboxylic acid (CAS 760174-11-6)
- 2-(Difluoromethyl)pyridin-4-ol (CAS 501125-75-3)
- 6-(3-Aminopyrrolidin-1-yl)-1,2,4-triazine-3,5(2H,4H)-dione hydrochloride (CAS 2138018-74-1)
- 1-(3-Bromo-5-chloro-2-methoxyphenyl)-N-methylmethanamine (CAS 1082945-36-5)
- (5-Bromopyridin-3-yl)(p-tolyl)methanol (CAS 1249074-30-3)
- 5-(1-(Hydroxyamino)ethylidene)pyrimidine-2,4(3H,5H)-dione (CAS 1905453-18-0)
- Methyl 1-(3-bromophenyl)cyclopropane-1-carboxylate (CAS 749928-59-4)
- 1-Bromo-2-fluoro-4-(4-methoxybenzyl)benzene (CAS 2432848-65-0)
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- 3-Fluoro-5-(pentafluoro-lambda6-sulfanyl)benzaldehyde (CAS 1240257-92-4)
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Why CATO?
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