Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate CAS 899684-01-6

Purity 97%+In StockPharmaceutical Standards
CAS No.899684-01-6
Molecular FormulaC14H14ClNO2S
Molecular Weight295.78 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate CAS 899684-01-6 chemical structure

Description

The occurrence of Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate (CAS 899684-01-6), a certified reference material (molecular formula C14H14ClNO2S, MW 295.78 g/mol) for analytical method development and quality control.

The molecular framework of Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate (C14H14ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H14ClNO2S
Molecular Weight295.78 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

Related Ethyl Standards

Recommended Standards

Why CATO?