Propyl 2-amino-4-(2-chlorophenyl)thiophene-3-carboxylate CAS 351158-61-7
| CAS No. | 351158-61-7 |
| Molecular Formula | C14H14ClNO2S |
| Molecular Weight | 295.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Propyl 2-amino-4-(2-chlorophenyl)thiophene-3-carboxylate (C14H14ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Propyl 2-amino-4-(2-chlorophenyl)thiophene-3-carboxylate (CAS 351158-61-7), a certified reference material (molecular formula C14H14ClNO2S, MW 295.78 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Propyl 2-amino-4-(2-chlorophenyl)thiophene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14ClNO2S |
| Molecular Weight | 295.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Propyl Standards
- Ethyl 2-amino-5-(2-chlorophenyl)-4-methylthiophene-3-carboxylate (CAS 1213791-75-3)
- Ethyl 2-amino-4-(3-chlorophenyl)-5-methylthiophene-3-carboxylate (CAS 350989-54-7)
- Ethyl 2-amino-4-(4-chloro-3-methylphenyl)thiophene-3-carboxylate (CAS 899684-01-6)
- Ethyl 2-amino-4-(4-chlorophenyl)-5-methylthiophene-3-carboxylate (CAS 350989-77-4)
- Ethyl 2-amino-5-(2-chlorobenzyl)thiophene-3-carboxylate (CAS 848081-09-4)
- Propyl 2-amino-4-(4-chlorophenyl)thiophene-3-carboxylate (CAS 350997-20-5)
- 1-(4-(2-Amino-4-chlorophenyl)piperazin-1-yl)-3-methylbutan-1-one (CAS 879590-35-9)
- 1-(4-(4-Amino-2-chlorophenyl)piperazin-1-yl)-2,2-dimethylpropan-1-one (CAS 878441-21-5)
Recommended Standards
- N-[2-(chloromethyl)-phenyl]-4-methylbenzene-1-sulfonamide (CAS 243844-35-1)
- N-(5-chloro-2-methylphenyl)-4-methylbenzenesulfonamide (CAS 55816-01-8)
- Clopidogrel Impurity 82 (CAS 1015247-87-6)
- N-(4-Chlorophenyl)-2,5-dimethylbenzenesulfonamide (CAS 71796-20-8)
- 2-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 837392-54-8)
- Ethyl 2-(6-bromopyridin-3-yl)-2-oxoacetate (CAS 745816-48-2)
- 4-(2-Fluorophenyl)-1-methylpiperidin-4-ol (CAS 72365-19-6)
- fluoro-Dapagliflozin (CAS 1181681-43-5)
- Acetamide, N-(2-bromo-5-pyrimidinyl)- (CAS 1209458-44-5)
- 2-(Benzylsulfonyl)-N-hydroxyacetimidamide (CAS 1242336-23-7)
- 5,6-Chrysenequinone (CAS 2051-10-7)
- 2,3-Dichloro-4-(difluoromethoxy)benzodifluoride (CAS 1804516-12-8)
- 2-(Chloromethyl)-1,4-naphthalenedione (CAS 43027-41-4)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
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