2'-Chloro-[1,1'-biphenyl]-3-amine CAS 90-28-8
| CAS No. | 90-28-8 |
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2'-Chloro-[1,1'-biphenyl]-3-amine (CAS 90-28-8), molecular formula C12H10ClN and molecular weight 203.67 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2'-Chloro-[1,1'-biphenyl]-3-amine (C12H10ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 203.67 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-phenylaniline (CAS 101-17-7)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- 2-Chloro-4-(4-methylphenyl)pyridine (CAS 1202574-24-0)
- 2'-Chloro-[1,1'-biphenyl]-2-amine (CAS 1203-43-6)
- 2'-Chloro-[1,1'-biphenyl]-4-amine (CAS 1204-42-8)
- 2-Chloro-4-methyl-5-phenylpyridine (CAS 1214335-53-1)
- 2-Chloro-3-methyl-4-phenylpyridine (CAS 1221719-00-1)
- 4-chloro-5,5-dimethyl-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one (CAS 1226804-02-9)
Recommended Standards
- 2-Benzyl-6-chloropyridine (CAS 74714-04-8)
- 2-Chloro-[1,1'-biphenyl]-3-amine (CAS 1997842-72-4)
- 2-amino-7-chloro-3,4-dihydroquinazolin-4-one (CAS 20198-18-9)
- 2-Chloro-3-cyclopropylquinoline (CAS 85274-12-0)
- Ethyl 2-(3,6-dimethylpyridin-2-yl)acetate (CAS 1393532-01-8)
- 2,2-Difluoroethyl 4-methylbenzenesulfonate (CAS 135206-84-7)
- 6-Bromobenzo[e][1,2,3]oxathiazine 2,2-dioxide (CAS 115540-65-3)
- 5-bromo-4-chloro-6-methylthieno[2,3-d]pyrimidine (CAS 1388892-94-1)
- 3-Bromo-5-nitro-2-(piperidin-1-yl)pyridine (CAS 1065074-87-4)
- (-)-Ageloxime D (CAS 1219817-25-0)
- 2-((Tert-butoxycarbonyl)amino)-2-methylcyclohexane-1-carboxylic acid (CAS 1423028-83-4)
- 4-(2,2-Difluoroethoxy)-3-trifluoromethylbenzaldehyde (CAS 1486100-65-5)
- 2-Bromo-4-methyl-3-nitrophenol (CAS 74129-08-1)
- Neuropeptide S (human) (CAS 412938-67-1)
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