Estrone 17-Ethylene ketal CAS 900-83-4
| CAS No. | 900-83-4 |
| Molecular Formula | C20H26O3 |
| Molecular Weight | 314.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Estrone 17-Ethylene ketal.
Estrone 17-Ethylene ketal (CAS 900-83-4), molecular formula C20H26O3 and molecular weight 314.42 g/mol, is a CATO reference standard with documented purity and traceability.
Estrone 17-Ethylene ketal (C20H26O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Estrone 17-Ethylene ketal meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H26O3 |
| Molecular Weight | 314.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Estrone Standards
- Estrone Impurity 12 (CAS CATO-C4X-210512)
- Estrone Impurity 11 (CAS CATO-C4X-210511)
- Estrone 16-Oxime (CAS 6038-23-9)
- Estrone 3-Methyl Ether (CAS 1624-62-0)
- Estrone Impurity 10 (CAS CATO-C4X-210510)
- Estrone Impurity 13 (CAS CATO-C4X-210513)
- Estrone 3,4-quinone (CAS 40551-34-6)
- Estrone 3-O-Sulfamate (CAS 148672-09-7)
Recommended Standards
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- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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