7-(2-Chloro-6-fluorobenzyl)-6,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazine CAS 900015-06-7
| CAS No. | 900015-06-7 |
| Molecular Formula | C14H12ClFN4 |
| Molecular Weight | 290.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(2-Chloro-6-fluorobenzyl)-6,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 900015-06-7) is a high-purity analytical reference standard with the molecular formula C14H12ClFN4 and a molecular weight of 290.72 g/mol.
The molecular framework of 7-(2-Chloro-6-fluorobenzyl)-6,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazine (C14H12ClFN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-(2-Chloro-6-fluorobenzyl)-6,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12ClFN4 |
| Molecular Weight | 290.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- 4-((4-Chlorophenyl)thio)-3-nitrobenzonitrile (CAS 27917-77-7)
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- 2-(2-chloro-4-fluorophenoxymethyl)-8-methylimidazo[1,2-a]pyridine (CAS 871218-91-6)
- Hydrochlorothiazide Impurity 22 (CAS 90794-87-9)
- (1S,3S)-1-(Hydroxymethyl)-3-(tritylamino)cyclopentanol (CAS 1113025-25-4)
- 8-Bromopyrido[3,4-d]pyridazine (CAS 40511-78-2)
- Methyl 5-bromothieno[2,3-b]pyridine-2-carboxylate (CAS 1250443-94-7)
- (Z)-4-(4-nitrobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 57427-80-2)
- 2-(4-Nitrophenoxy)pyrimidine (CAS 181801-29-6)
- tert-Butyl 4-(Aminomethyl)-3-fluoropiperidine-1-carboxylate (CAS 1303972-96-4)
- 4-(2-Chloroethyl)-N,N-diethylbenzenesulfonamide (CAS 1018537-40-0)
- 5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)thiophene-2-carbaldehyde (CAS 1706455-93-7)
- 3-Chloro-1-phenethyl-1H-1,2,4-triazole hydrochloride (CAS 1279219-39-4)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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