4-(2,4,5-Trichlorophenyl)-1,3-thiazol-2-amine CAS 900640-48-4
| CAS No. | 900640-48-4 |
| Molecular Formula | C9H5Cl3N2S |
| Molecular Weight | 279.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(2,4,5-Trichlorophenyl)-1,3-thiazol-2-amine (C9H5Cl3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-(2,4,5-Trichlorophenyl)-1,3-thiazol-2-amine (CAS 900640-48-4), a certified reference material (molecular formula C9H5Cl3N2S, MW 279.57 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(2,4,5-Trichlorophenyl)-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl3N2S |
| Molecular Weight | 279.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trichlorophenyl Standards
- 4-(2,3,4-Trichlorophenyl)thiazol-2-amine (CAS 123971-41-5)
- 4-Oxo-4-(3,4,5-trichlorophenyl)butanoic acid (CAS 62903-19-9)
- 5-Methyl-1-(2,4,5-trichlorophenyl)-1H-pyrazol-3(2H)-one (CAS 14575-29-2)
- 3-Methyl-1-(2,4,6-trichlorophenyl)-1H-pyrazol-5(4H)-one (CAS 14657-25-1)
- (5-(2,4,5-Trichlorophenyl)furan-2-yl)methanol (CAS 773870-51-2)
- 3-Methyl-1-(2,4,6-trichlorophenyl)-1H-pyrazol-5-amine (CAS 106259-87-4)
- 1-(2,4,6-Trichlorophenyl)-1H-pyrrole-2,5-dione (CAS 13167-25-4)
- 1-(2,4,5-Trichlorophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 31489-22-2)
Recommended Standards
- N-Benzyl-1-(trimethylsilyl)-N-((trimethylsilyl)methyl)methanamine (CAS 144964-17-0)
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