5-(2-Chloroethyl)-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione CAS 90301-61-4
| CAS No. | 90301-61-4 |
| Molecular Formula | C11H15ClN2O5 |
| Molecular Weight | 290.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Chloroethyl)-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 90301-61-4), molecular formula C11H15ClN2O5 and molecular weight 290.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(2-Chloroethyl)-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (C11H15ClN2O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(2-Chloroethyl)-1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15ClN2O5 |
| Molecular Weight | 290.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroethyl Standards
- 5-(2-Chloroethyl)-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 90301-59-0)
- 2-(1-Chloroethyl)-5-phenyl-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 733030-57-4)
- 2-Chloroethyl tetradecanoate (CAS 51479-36-8)
- 3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid (CAS 6746-11-8)
- 9-((2-Chloroethyl)sulfinyl)acridine (CAS 827303-16-2)
- N-(2-Chloroethyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]urea (CAS 1987135-73-8)
- 4'-[Bis(2-Chloroethyl)Amino]-2-Fluoroacetanilide (CAS 1492-93-9)
- 1-((4-(2-Chloroethyl)phenyl)sulfonyl)piperidine (CAS 1018334-04-7)
Recommended Standards
- 5-Formyl-2-methoxyphenyl 2-chlorobenzoate (CAS 432016-56-3)
- 4-Formyl-2-methoxyphenyl 4-chlorobenzoate (CAS 321726-57-2)
- 5-Formyl-2-methoxyphenyl 4-chlorobenzoate (CAS 431939-02-5)
- 4-Formyl-2-methoxyphenyl 2-chlorobenzoate (CAS 321726-59-4)
- 4-(4-Chlorobenzyl)-7-methoxyisoquinoline (CAS 61189-85-3)
- 2-Oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carbaldehyde (CAS 1553231-99-4)
- Methyl 4'-fluoro-1,1'-biphenyl-4-carboxylate (CAS 80254-87-1)
- 7-(2H-1,3-Benzodioxol-5-yl)-2-(methylsulfanyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 439108-52-8)
- 1-2-3-4-Tetra-O-benzyl-β-D-glucopyranoside (CAS 27851-29-2)
- 2-Methyl-5-(3-nitro-phenyl)-[1,3,4]oxadiazole (CAS 122733-39-5)
- 2′-Methoxy-5′-methyl[1,1′-biphenyl]-3-carboxylic acid (CAS 1181381-20-3)
- 1-Methyl-1,4,5,6-tetrahydropyridine-2-carboxylic acid (CAS 861589-49-3)
- 6-((2,2-Dimethoxyethyl)amino)pyrimidin-4-ol (CAS 1696136-35-2)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com