3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid CAS 6746-11-8
| CAS No. | 6746-11-8 |
| Molecular Formula | C13H17Cl2NO2 |
| Molecular Weight | 290.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid.
3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid (CAS 6746-11-8) is a high-purity analytical reference standard with the molecular formula C13H17Cl2NO2 and a molecular weight of 290.19 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 290.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-(Bis(2-chloroethyl)amino)phenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H17Cl2NO2 |
| Molecular Weight | 290.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
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- N-(2-Chloroethyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]urea (CAS 1987135-73-8)
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Recommended Standards
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- (5E)-5-(3,4-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 6326-22-3)
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- 5'-(2-Formylphenyl)-[1,1':3',1''-terphenyl]-2,2''-dicarbaldehyde (CAS 87226-90-2)
- 2-((4-Chlorophenyl)amino)-6-methylpyrimidin-4(3H)-one (CAS 50427-11-7)
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