Loxoprofen Impurity 154 CAS 90319-74-7
| CAS No. | 90319-74-7 |
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Loxoprofen Impurity 154 (C15H18O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Loxoprofen Impurity 154 (CAS 90319-74-7, C15H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loxoprofen Impurity 154 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18O3 |
| Molecular Weight | 246.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
Related Loxoprofen Standards
- Loxoprofen Impurity 147 (CAS CATO-C4X-1488147)
- Loxoprofen Impurity 148 (CAS CATO-C4X-1488148)
- Loxoprofen Impurity 155 (CAS 90319-73-6)
- Loxoprofen Impurity 156 (CAS 83599-42-2)
- Loxoprofen Impurity 157 (CAS 90319-78-1)
- Loxoprofen (CAS 68767-14-6)
- m-Loxoprofen (CAS 1026471-88-4)
- o-Loxoprofen (Mixture of Diastereomers) (CAS 1027400-34-5)
Recommended Standards
- Busulfan impurity 26 (CAS CATO-C4X-145526)
- Busulfan (CAS 55-98-1)
- Citalopram Impurity 93 (CAS CATO-C4X-110993)
- Fexofenadine Impurity 18 (CAS 880088-78-8)
- Ruxolitinib Impurity 189 (CAS 2761879-51-8)
- Lansoprazole Impurity 50 (CAS 116418-99-6)
- Tazobactam lmpurity 29 (CAS 80353-26-0)
- 3-(Aminomethyl)-N-methyl-1,2,4-oxadiazole-5-carboxamide hydrochloride (CAS 1185020-61-4)
- n-Ethyl-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine (CAS 930482-25-0)
- 5-(4-Bromophenoxy)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 882228-97-9)
- 2-((2-(1H-pyrrol-1-yl)phenyl)thio)-3-chloro-5-(trifluoromethyl)pyridine (CAS 338406-74-9)
- n-(4-Aminophenyl)furan-2-carboxamide (CAS 21838-58-4)
- (1-Ethyl-4-methyl-1H-imidazol-5-yl)methanol (CAS 1256560-93-6)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com