Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) CAS 90357-51-0
| CAS No. | 90357-51-0 |
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) (CAS 90357-51-0), a pharmacopoeial impurity reference standard (molecular formula C12H9F3N2O2, MW 270.21 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) (C12H9F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bicalutamide Standards
- Bicalutamide Impurity 10 (CAS 367-67-9)
- Bicalutamide Impurity 21 (CAS 71515-96-3)
- Bicalutamide Impurity 34 (CAS CATO-C4X-101334)
- Bicalutamide EP Impurity M (CAS 151262-57-6)
- Bicalutamide Impurity 22 (CAS 405-31-2)
- Bicalutamide Impurity 13 (CAS 90357-53-2)
- Bicalutamide Impurity 23 (CAS 2905-15-9)
- Bicalutamide Impurity 20 (CAS 316373-92-9)
Recommended Standards
- 5-Ethynyl-1-(3-fluoro-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione 5-ethynyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione 95740-26-4 (CAS 95740-26-4)
- Nilotinib Impurity 16 (CAS 641571-13-3)
- N-Methyl-2-(3-(trifluoromethyl)isoxazol-5-yl)benzamide (CAS 62039-95-6)
- Leflunomide (CAS 75706-12-6)
- Dotinurad Impurity 99 (CAS CATO-C4X-249499)
- Abiraterone Impurity N8 (CAS 2487-48-1)
- Finerenone Impurity 267 (CAS CATO-C4X-2880267)
- (3-Methoxy-1-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)methanol (CAS 1701434-10-7)
- 7-(Benzyloxy)-4-bromo-6-methoxyquinoline (CAS 1251032-69-5)
- Benzyl(R)-(2,5-dioxopyrrolidin-3-yl)carbamate (CAS 179747-84-3)
- 5-bromo-3-iodo-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 934568-22-6)
- 2-(6,10-Dithiaspiro[4.5]decan-1-yl)isonicotinic acid (CAS 1706452-07-4)
- 4-((4-Aminophenyl)amino)-6-ethoxy-1,3,5-triazin-2(1H)-one (CAS 62808-06-4)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com