Phytomenadione/Vitamin K1 Impurity 80 CAS CATO-C4X-220780
| CAS No. | CATO-C4X-220780 |
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Phytomenadione/Vitamin K1 Impurity 80 (CAS CATO-C4X-220780), a pharmacopoeial impurity reference standard (molecular formula C14H12O4, MW 244.24 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Phytomenadione/Vitamin K1 Impurity 80 (C14H12O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Phytomenadione Standards
- Phytomenadione/Vitamin K1 Impurity 125 (CAS 49802-39-3)
- Phytomenadione/Vitamin K1 Impurity 79 (CAS CATO-C4X-220779)
- Phytomenadione/Vitamin K1 Impurity 124 (CAS CATO-C4X-2207124)
- Phytomenadione/Vitamin K1 Impurity 81 (CAS CATO-C4X-220781)
- Phytomenadione/Vitamin K1 Impurity 88 (CAS CATO-C4X-220788)
- Phytomenadione/Vitamin K1 Impurity 82 (CAS CATO-C4X-220782)
- Phytomenadione/Vitamin K1 Impurity 115 (CAS CATO-C4X-2207115)
- Phytomenadione/Vitamin K1 Impurity 116 (CAS CATO-C4X-2207116)
Recommended Standards
- Levothyroxine Impurity 53 (CAS CATO-C4X-167853)
- Roxadustat Impurity 42 (CAS CATO-C4X-221342)
- Formoterol impurity 112 (CAS 63192-58-5)
- 2,2＇-Dihydroxy-4-methoxybenzophenone (CAS 131-53-3)
- Azacitidine Impurity 11 (CAS CATO-C4X-138811)
- Epinastine Impurity 22 (CAS 124847-00-3)
- Vinorelbine EP Impurity D (CAS CATO-C4X-26425)
- Ethyl 2-(5-chloro-2-ethoxy-4-formylphenoxy)acetate (CAS 690992-01-9)
- 7-Oxa-1-azaspiro[4.5]Decane (CAS 82742-26-5)
- 4-Bromo-3-(4-nitrophenyl)-1H-pyrazole (CAS 73227-97-1)
- Fibrinogen Related Peptide (CAS 80755-86-8)
- Ethyl 3-(tert-butoxymethyl)-1H-pyrazole-4-carboxylate (CAS 518990-19-7)
- N,N-Diphenyl-[2,2':5',2''-terthiophen]-5-amine (CAS 888488-90-2)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com