(1S,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane CAS 905454-52-6
| CAS No. | 905454-52-6 |
| Molecular Formula | C18H19FO5S |
| Molecular Weight | 366.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (1S,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane.
CATO supplies (1S,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane (CAS 905454-52-6), a certified reference material (molecular formula C18H19FO5S, MW 366.40 g/mol) for analytical method development and quality control.
The molecular framework of (1S,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane (C18H19FO5S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (1S,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19FO5S |
| Molecular Weight | 366.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- (1R,2S)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane (CAS 303176-40-1)
- 4-((4-(Imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl)amino)benzenesulfonamide (CAS 328061-37-6)
- (1R,2R)-2-(2-Tosyl-1,2-dihydroxyethyl)-6-fluorochromane (CAS 303176-46-7)
- 5,8-Difluoro-3,3,4,4-tetramethyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918645-76-8)
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