Clofazimine EP Impurity A CAS 90690-85-0
| CAS No. | 90690-85-0 |
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Clofazimine EP Impurity A is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Clofazimine EP Impurity A (CAS 90690-85-0) is a certified pharmaceutical impurity reference standard with the molecular formula C24H16Cl2N4HCl and a molecular weight of 467.78 g/mol.
Clofazimine EP Impurity A (C24H16Cl2N4HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clofazimine EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16Cl2N4 HCl |
| Molecular Weight | 467.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 3 (CAS 103051-26-9)
- Clofazimine Impurity 8 (CAS 138452-44-5)
- Clofazimine (CAS 2030-63-9)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
- Clofazimine Impurity 5 (CAS 23008-56-2)
- Clofazimine Impurity 6 (CAS 24028-59-9)
- Clofazimine Impurity N2 (CAS 24396-82-5)
Recommended Standards
- Letermovir Impurity 50 (CAS CATO-C4X-291550)
- Upadacitinib Impurity 95 (CAS CATO-C4X-240595)
- Famotidine Impurity 57 (CAS 95853-46-6)
- (3-Nitropyridin-2-yl)methanamine (CAS 1824097-41-7)
- 6,6'-Bis(bromomethyl)-2,2'-bipyridine (CAS 96517-97-4)
- {2-[(chlorocarbonyl)oxy]ethanesulfonyl}methane (CAS 53298-29-6)
- 6-Amino-3-ethylindolin-2-one (CAS 23694-70-4)
- 2,3-dimethyl-2H-indazole-6-carboxylic acid (CAS 1234616-78-4)
- (S)-4-[4-(Boc-amino)butyl]oxazolidine-2,5-dione (CAS 33043-60-6)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com