Thiotepa Impurity 1 CAS 90877-51-3
| CAS No. | 90877-51-3 |
| Molecular Formula | C6H13ClN3PS |
| Molecular Weight | 225.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Thiotepa Impurity 1.
CATO supplies Thiotepa Impurity 1 (CAS 90877-51-3), a pharmacopoeial impurity reference standard (molecular formula C6H13ClN3PS, MW 225.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H13ClN3PS, Thiotepa Impurity 1 contains sulfur-containing functionality, organophosphorus functionality, chlorine substitution; these features give the compound characteristic molecular-ion distribution patterns in mass spectrometry. The molecular weight of 225.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H13ClN3PS |
| Molecular Weight | 225.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.5 |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiotepa Standards
- Thiotepa Impurity 12 (CAS 2835499-20-0)
- Thiotepa Impurity 4 (CAS CATO-C4X-21564)
- Thiotepa Impurity 2 (CAS 121258-29-5)
- Thiotepa Impurity 6 (CAS CATO-C4X-21566)
- Thiotepa Impurity 13 (CAS 1879073-27-4)
- Thiotepa Impurity 5 (CAS CATO-C4X-21565)
- Thiotepa Impurity 14 (CAS CATO-C4X-215614)
- Thiotepa Impurity 11 (CAS CATO-C4X-215611)
Recommended Standards
- N-butyl-5-chloro-1H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 2750883-29-3)
- (4-(2-Chlorophenyl)thiazol-2-yl)methanol (CAS 1050507-07-7)
- N2,N2-Diallyl-6-chloro-1,3,5-triazine-2,4-diamine (CAS 857977-79-8)
- 2-Chloro-n-(1,1-dioxo-1λ6-thian-4-yl)acetamide (CAS 1107645-27-1)
- All-rac-alfa-Tocopherol EP Impurity B (Mixture of Diastereomers) (CAS CATO-C4X-119515)
- Amorolfine Impurity 13(Isomer mixture) (CAS 74880-04-9)
- Evocalcet Impurity 19 (CAS 2851537-36-3)
- 1-n,1-n-Dimethyl-4-n-(quinolin-2-ylmethyl)benzene-1,4-diamine (CAS 62257-13-0)
- Lauryl dimethylamine oxide (30% in water) (CAS 70592-80-2)
- Tert-butyl (3-isobutyramidophenyl)carbamate (CAS 925610-53-3)
- 2-Amino-4,5-dimethoxybenzaldehyde (CAS 22608-87-3)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-isopropylphenyl)propanoic acid (CAS 1260613-55-5)
- (2E)-2-({[(4-methoxyphenyl)methyl]amino}methylidene)-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 338416-81-2)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
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