Meloxicam impurity 14 CAS 91-25-8
| CAS No. | 91-25-8 |
| Molecular Formula | C7H5O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Meloxicam impurity 14 (C7H5O4SNa) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Meloxicam impurity 14 (CAS 91-25-8, C7H5O4SNa) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5O4S Na |
| Molecular Weight | 208.16 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Meloxicam Standards
- Meloxicam Impurity 1 (CAS 101855-37-2)
- Meloxicam Impurity 8 (CAS 125372-22-7)
- Meloxicam EP Impurity C (CAS 1262333-25-4)
- Meloxicam impurity 13 (CAS 130262-92-9)
- Meloxicam Impurity 9 (CAS 13165-80-5)
- Meloxicam EP Impurity D (CAS 1331636-17-9)
- Meloxicam Impurity 11 (CAS 1865298-74-3)
- Meloxicam Impurity 16 (CAS 39122-64-0)
Recommended Standards
- Ferulic Acid Impurity 1 (CAS 2931-90-0)
- Peramivir Impurity 87 (CAS CATO-C4X-183387)
- Fenoterol Impurity 8 HBr (CAS CATO-C4X-20778)
- 3-Methyl-5-(n-methylacetamido)isothiazole-4-carboxylic acid (CAS 1521168-62-6)
- Valsartan impurity 7 (CAS 914465-68-2)
- 4-Chloro-2-cyclohexyl-6-methylpyrimidine (CAS 94052-09-2)
- 2-(Trifluoromethyl)morpholine Hydrochloride (CAS 1196152-51-8)
- 1-((4-Ethylcyclohexyl)amino)-2-methylpropan-2-ol (CAS 1248933-71-2)
- 3-(3-(Difluoromethoxy)phenyl)-1,2,4-oxadiazole-5-carbaldehyde (CAS 1708400-78-5)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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